SUBJECT INDEX 



761 



effect on pantothenic acid require- 

 ment, 684 



fatty liver and, 20, 87 



in choline deficiency, 72, 129 

 Prothrombin, 418, 419 



dicoumarol and, 413 



in vitamin deficiency, 389, 432-435 



site of formation, 400-401 



vitamin K and, 400 

 Prothrombin factor, see Vitamin K 

 Prothrombin-time, in vitamin K assay, 



407-408 

 Provitamins D, activatability of, 143-146 



biogenesis, 156-159 



chemistrjf of activation, 179-203 



history, 138-140 



irradiation of, 138-140 



isolation of, 148-152 



of invertebrates, 155-156 



physics of activation, 173-179 



syntheses, 140-143, 146, 148 

 Provitamin Dm, properties of, 205 

 Provitamin Do , 135 

 Provitamin D3 , 135 

 Pseudocholinest erase, 



acetylcholine and, 17 



choline and, 91 

 Pteroylglutamic acid, see Folic acid 

 Ptyaline, 235 

 Pyridine, 



liver fat and, 74 



niacin synthesis from, 475 



toxicity of, 572 

 2,3-P3'ridinedicarboxylic acid, niacin 



formation from, 473 

 3,4-Pyridinedicarboxylic acid, niacin 



formation from, 473 

 Pyridine-3-carboxylic acid, see Niacin 

 4-Pyridinecarboxylic acid, 473 

 Pyridine nucleotides, 625 



apoenzymes of, 491-492 



biochemical reactions of, 494-504 



destruction of, 507-508 



estimation of, 537-538 



high-energ}^ phosphate and, 496-498 



holoenzymes of, 492 



inhibition of, 508-509 



in lipid metabolism, 501-502 



in niacin deficiency, 555 



in nitrogen metabolism, 502-503 



in pentose biosynthesis, 500-501 



in photosynthesis, 503-504 



inteiconversion of, 493 



mechanism of action, 490-491 



occurrence of, 484 

 _ semiquinoid intermediates of, 491 



specificity of, 493-494 

 Pyridine-3-sulfonic acid, 



as inhibitor, 508, 549-550 



synthesis of, 475, 478 

 Pyridoxine, 101, 380, 653, 656, 657 



deficiency, 283-285 



effect on niacin requirement, 529, 584- 

 585 



fatty acids and, 315-316 



fatty liver and, 82, 90 



in inositol deficiency, 368 



in methyl synthesis, 85 

 Pyrocalciferol, 



as provitamin D, 144 



formation of, 142, 196 

 Pyrophosphatase, 15 



coenzyme A and, 632 

 Pyrrole, 625 



synthesis of, 622 

 Pyruvic acid, 17, 509, 510, 511 



as inositol precursor, 355 



formation from inositol, 349 



in acetyl transfer, 617 



in pantothenic acid deficiency, 662 



oxidation of, 625 



pantothenic acid and, 598, 679 



pyridine nucleotides and, 498-500 



Quebrachitol, occurrence of, 336, 363 



Quercitols, 329 



Quinic acid, 363 



Quinine, vitamin K and, 426 



Quinoline, 



in industrial niacin production, 478-479 



liver fat and, 74 

 Quinolinic acid, 



activity of, 521 



in niacin sj'nthesis, 473, 475, 526, 528 

 Quinone, 



in dehydrogenation of cholesterol, 147- 

 148 



Rabbit, niacin deficiency in, 569 

 Rachitamin, 132 



