762 



SUBJECT INDEX 



Rachitastero], 132 



Radiophosphorus, in vitamin D estima- 

 tion, 220 

 Rat, 

 fatty acid deficiency in, 292-295, 306, 



314 

 in pantothenic acid assay, 629 

 niacin synthesis in, 526-529 

 pantothenic acid deficiency in, 650-658 

 pathology of niacin deficiency, 568-569 

 Reineckate, in choline estimation, 53-54 

 Reineckate procedure, in choline isola- 

 tion, 6 

 Renal disease, effect on rickets, 260 

 Reproduction, on fat -free diet, 293, 316 

 Reproductive organs, in fatty acid de- 

 ficiency, 299 

 Rhodopsin, 563 



Riboflavin, 445, 497, 567, 653, 677 

 burning feet syndrome and, 677 

 choline oxidase and, 38, 87 

 fatty acids and, 286 

 fatty liver and, 80 

 in pellagra, 553 

 leucocytes and, 91 

 niacin and, 555, 562, 585 

 pantothenic acid and, 637, 690 

 porphyrin and, 656 

 Ribonuclease, in osteoblasts, 237 

 Ribonucleic acid, in osteoblasts, 237 

 Ribose, in diphosphopyridine nucleo- 

 tide, 485 

 Ribose-5-phosphate, biosjaithesis of, 



500-501 

 Ribs, in rickets, 238-239 

 Ribulose phosphate, 501 

 in photosynthesis, 503 

 Rickets, 132-133, see also Vitamin D de- 

 ficiency 

 acidity of intestinal contents in, 229- 



230 

 bone ash in, 230 

 bone changes in, 227-228 

 external appearance, 224-225 

 histological changes in, 231-232, 241- 



247 

 in adults, 241 (see Osteomalacia) 

 in infants, 238-240 

 production in rats, 223-224 

 serum calcium and phosphorus in, 225- 

 226 



Raniacol, 574 



Rubber, biosynthesis of, 625 



Salicylic acid, 

 as inhibitor, 508 

 prothrombin and, 418, 432 

 vitamin K and, 439 

 Sarcosine, see also Monomethylglycine 

 as methyl donor, 28 

 conversion to glyoxylate, 42 

 in creatine formation, 31 

 in growth of microorganisms, 50, 55 

 perosis and, 97 

 Sarcosine oxidase, 

 ethionine and, 39 

 vitamin B12 and, 85 

 Scurvy, 673-674 

 differentiation from vitamin K de- 

 ficiencj', 420 

 Scyllitol, 322, 323, 324, 338 

 occurrence of, 335, 363 

 vitamin activity of, 352-353 

 Sedoheptulose, 501 

 Seeds, pantothenic acid in, 636 

 Selenite, methylation of, 44, 51 

 Semicarbazide, effect on choline oxidase, 



36 

 Sequoitol, 334 

 Serine, 



as source of formate, 42 

 decarboxj'lation of, 42-43 

 in aminoethanol formation, 84 

 in choline formation, 43, 71, 79 

 in methyl carbon oxidation, 43-44 

 in methyl group synthesis, 27 

 methionine toxicity and, 95 

 synthesis of, 27, 28, 41 

 Serine dehydrase, in glycine formation, 



42 

 Sex hormones, 134 

 Shikimic acid, 363 

 Silicotungstic acid, 

 in acetylcholine isolation, 8 

 in choline isolation, 7 

 Sinkaline, 3 

 Sitostanol, 135 

 Sitosterol, 135, 143 

 dehydrogenation of, 146-147 

 irradiation of, 138-139 



