CONTENTS 



E. Broda: Die Entstehung des dynamischen Zustandes 334 



M. Grunberg-Manago : Synthèse enzymatique des ribopolynucléotides 344 



A. E. Mirsky: A note on the evolution of nucleic acids 358 



J. Brächet: Les acides nucléiques et l'origine des protéines 361 



Discussion (Chairman : O. Hoffmann- Ostenhof) 368 



A. I. Oparin,* I. MÂLEK,* E. N. Pavlovskiî,* N. W. Pirie, A. A. Smorodintsev,* 

 H. L. Fraenkel-Conrat,* W. M. Stanley,* L. A. Zil'ber,* V. Ryzhkov,* 

 A. N. Belozerskiï,* G. Schramm,* V. S. Tongur,* S. E. Bresler,* 

 A. S. KoNiKOVA,* M. Grunberg-Manago, K. G. Ioffe,* N. I. Nuzhdin* 



Fifth Session (Chairman : M. Grxjnberg-Manago) 

 The Origin of Structure and Metabolism 



Reports 



J. D. Bernal: The scale of structural units in biopoesis 385 



N. M. Sisakyan : The part played by structural elements in the biochemical function 



of cells* 400 



I. Prigogine: Problèmes d'évolution dans la thermodynamique des phénomènes 



irreversibles (read at Sixth Session) 418 



Communications 



A. I. Oparin: Biochemical processes in the simplest structures 428 



P. Mitchell: The origin of life and the formation and organizing functions of 



natural membranes 437 



A. G. Pasynskiï: Enzymic reactions in stationary open systems* 444 



F. B. Straub: Biosynthesis of enzymes and their origin 455 

 R. Khesin : Cell structure and protein synthesis 460 

 E. Macovschi: Some relationships between coacervates and enzymes* 466 



G. A. Deborin : Protein complexes as biochemically active systems 470 



Discussion (Chairman: F. B. Straub): 480 



K. MOTHES, O. B. LePESHINSKAYA,* M. V. VOL'KENSHTEINf,* 



A. G. PASYNSKn,*t K. S. TRINCHER,*t Zh. ÏORDANOV,* G. M. FRANK,* S. W. FoX, 



p. SOKOL,* T. N. EVREINOVA,* V. I. VOROBIEV,* G. P. Kalina,* M. I. Gol'din,* 



R. L. Berg,* V. S. Tongur,* B. S. Diskina,* J. D. Bernal,* I. Prigogine*! 



(tContributed at Sixth Session) 



Sixth Session (Chairman : K. Felix) 

 The Evolution of Metabolism 



Reports 



M. Florkin: L'extension de la biosphère et l'évolution biochimique 503 



V. N. Shaposhnikov: Über einige wahrscheinliche Wege der Evolution des Stoff- 

 wechsels bei den Mikroorganismen 516 



A. E. Braunshtein : The pathways of biological assimilation and dissimilation of 



nitrogen and some aspects of their evolution 527 



Communications 

 V. L. Kretovich: Le rôle de l'ammoniaque dans l'assimilation autotrophe de l'azote 544 



