X CONTENTS 



VI. Growth of Mammals 218 



(a) Postembryonic growth, 218 - (b) Growth and hormones, 219 - (c) Em- 

 bryonic growth, 223 - 



VII. Relative Growth 224 



(a) The allometric equation, 224 - (b) Morphological applications of allo- 

 metry, 229 - (c) Physiological competition, 230 - (d) Biochemical applications, 

 232 - (e) Physiological applications, 232 - (f) Physiological and growth 

 gradients, 233 - (g) Growth of organs in time, 234 - 



\'III. Growth and Evolution 238 



(a) Transformation, 238 - (b) Evolutionary allometry, 240 - (c) Changes of 

 the organism-as-a-whole as growth problem, 245 - (d) The uniqueness of man 

 as a problem of growth, 247 - (e) Retardation, 248 - (f ) The evolution of the 

 brain, 250 - 



Literature 253 



Chapter 3. Nucleic Acids and Growth, by J. Bracket 260 



I. Introduction 260 



II. Brief Survey of Nucleic Acid Chemistry and Cellular Localization . . . 260 

 (a) Chemical composition, 260 - (b) Physical properties and molecular 

 structure, 261 - (c) Cytochemical techniques for detection, 262 - 



III. DNA and Growth: Mitosis 265 



(a) DNA content per cell nucleus, 265 - (b) Metabolic stability of DNA, 266 - 



(c) Genetic activity of DNA, 268 - (d) DNA synthesis during mitosis, 269 - 

 (e) Effects of physical and chemical agents on DNA and its synthesis, 271 - 



IV. RNA and Growth: Protein Synthesis 272 



(a) Cytochemical and quantitative evidence, 273 - (b) The role of RNA in plant- 

 virus multiplication, 276 - (c) Direct evidence for a role of RNA in growth 



and protein synthesis, 277 - (d) The mechanisms of protein synthesis, 284 - 



V. Nucleic Acids and Embryonic Development 285 



(a) Synthesis of DNA and RNA during development, 285 - (b) RNA and 

 morphogenesis, 288 - (c) The effects of an abnormal nuclear composition on 

 nucleic acids and development, 292 - 



VI. Final Remarks 293 



(a) Independence of DNA synthesis and protein synthesis, 293 - (b) The role 

 of the cell nucleus in growth and protein synthesis, 295 - (c) Nucleic acids and 

 regulation of growth, 297 - 



Literature 299 



Chapter 4. Germinal Organization and Induction Phenomena, by Albert 



M. Dalcq 305 



I. Organizing Aspects of Gametogenesis 3^6 



A. The cytoplasm of the gametes 3^6 



B. Growth and polarization of the oocytes 307 



C. Symmetrization during oogenesis 3^5 



II. Intrinsic Morphochoresis 3^9 



A. General trend and goal of intrinsic morphochoresis 319 



B. Fertilization and morphochoretic pattern 321 



