86 



INTERMEDIARY METABOLISM AND GROWTH 



TABLE 6 



TRANSAMINATION AND AMINO ACID SYNTHESIS 



Amino Acid 



Reaction 



1 . Glycine 



2. Serine 



Cysteine 



Glycine 



Tryptophane 



3. Cysteine 



4. Alanine 



5. Valine 



6. Leucine 



7. Isoleucine 



glyoxylate + glutamic ^ ' glycine + a-ketoglutaric 



hydroxypyruvate + alanine ' ^ serine + pyruvate 



phosphohydroxypyruvate + glutamic ^ — r phosphoserine + 



a-ketoglutaric 



P-sulfinylpyruvate + glutamic ' ' cysteinesulfinic + 



a-ketoglutaric 



pyruvate + glutamic ' alanine + a-ketoglutaric 



a-ketoisovalerate + glutamic ■' valine + a-ketoglutaric 



a-ketoisocaproate + glutamic leucine + a-ketoglutaric 



a-keto-p-methyl-valeric + glutamic ■' ^ isoleucine + 



a-ketoglutaric 

 a-ketobutyric + glutamic ' ' a-NH2-butyric + a-ketoglutaric 



oxalacetic + glutamic ^ » aspartic + a-ketoglutaric 



8. Aspartic 

 Isoleucine 

 Threonine-glycine 

 Methionine 

 Homoserine 



9. Glutamic 

 Proline 



Ornithine-arginine 

 Hydroxyproline 



10. Ornithine-arginine glutamic-y-semialdehyde + glutamic " — ^ ornithine + 



a-ketoglutaric 



oxalacetic + glutamic ' ^ aspartic + a-ketoglutaric 



1 1 . Arginine 



12. Histidine 



13. Lysine 



14. Tyrosine 



N-acetyl glutamic semialdehyde + glutamic ' >■ N-acetyl- 



ornithine + a-ketoglutaric 



imidazoleacetal phosphate + glutamine ■' — ' histidinal phosphate 



+ a-ketoglutaric 



a-ketoadipic + glutamic ■' >■ a-aminoadipic + a-ketoglutaric 



/;-hydroxyphenylpyruvic + glutamic ' — r tyrosine + 



a-ketoglutaric 



15. Phenylalanine phenylpyruvic + glutamic •< ' phenylalanine + a-ketoglutaric 



