832 



THE CARCINOGENIC STIMULUS 



Fig. 1 8. Transplanted tumor (t) of the adrenal cortex. This tumor was induced in a Ce 



mouse by castration. The host was a castrated recipient. The stimulated seminal vesicles 



(s) demonstrate androgenic secretion by the transplanted tumor. The adrenals of the host 



are non-tumorous. 



Fig. 19. Effect of castration on the reproductive tract of strain A mice. This mouse had 



been ovariectomized one year before photography. The reproductive tract is atrophic. In 



other strains of mice castration provides the basis for development of neoplasia of the 



adrenal cortex (see Fig. 21). 



Fig. 20. Adrenal cortical carcinoma transplants (t) in castrated (left) and intact (right) 



male mice. Both transplants had been made at the same time several months before photo- 



Legends continued on p. 833 



