164 
17. Cote, WILLIAM. 
Adam in Eden. 1657. 
First edition. 
A rare herbal, in which the Doctrine of Signatures is carried to 
an extreme length. The author was a keen and enthusiastic col- 
lector of herbs. 
18. CoLoNNaA, FABio. 
| Phytobasanos| sive plantarwin aliquot historia. 159 
Iirst edition. 
The great feature of the book is the excellence of its descriptions 
and figures. The latter are noted as the first etchings on copper 
illustrating a botanical work. 
19. CoLtuMELLA, [L. J. M.] 
De re rustica libri xii... 1541. 
Born in the first century, at Cadiz, this celebrated Latin writer 
had a good practical knowledge of agriculture. His whole work 
is a treasury of information about ancient husbandry and the treat- 
ment of cultivated plants and trees. 
20. Cutpreper, Nicu [ovas | 
Pharmacopoeia Londinensis: or the London dispensatory 
6th edition. 
An exponent of astrological botany, Nicholas Culpeper became 
most unpopular with English physicians by publishing an unau- 
thorized edition of the Pharmacopeia, issuing it under various 
i : Ss 
titles. 
21. Cusa, Nicotaus pre. 1401-1464. 
Opera. Paris, 1514. 
In this book (Vol. I, folio NCVI) Cusanus (Niklas Krebs or 
Chrypffs) describes one of the first biological experiments of mod- 
ern times. He weighed seeds and planted them in 100 pounds of 
soil. Afterwards he weighed the soil and the plants that grew 
from the seed. Since the soil lost little in weight he concluded 
that the plants acquired most of their weight from the water which 
had been added to the soil; 137 years later van Helmont (q.v., 
No. 41) deseribed a similar experiment, “ pirated,” says Singer, 
from Cusanus. It was 213 years after Cusa before Hales, in his 
