No. 3-] NERVOUS SYSTEM OF CYNTHIA PARTITA. loi 



and 5 to 6 micra in length, with nuclei measuring 3X4 micra. 

 It can be seen that the nucleus is proportionally largest in the 

 smallest cells, therein frequently taking up a large part of the 

 cell-body. The nuclei of the smallest cells are much richer 

 in chromatic matter than are the nuclei of the larger cells, 

 and may easily be confounded with the so-called neuroglia 

 nuclei. 



Under the i-i2th oil immersion (Zeiss) the cell appears to 

 have a granulo-fibrillar structure. The granular masses, which 

 stain with haematoxylin and basic analins, are irregular in shape 

 and size, and look in places as if they were made up of smaller 

 granules. They are usually found concentrated in certain 

 regions of the cell, i.e., the extreme periphery, around the 

 nucleus, and sometimes near the center of the cell surrounding 

 the centrosome and sphere. A regular concentric grouping of 

 these granules was scarcely ever found. In general the larger 

 granules are found near the periphery of the cell. They are 

 frequently found forming a reticulum or arranged in rows. It 

 seems probable that these coarse granules are homologous with 

 the chromophilous substance of the vertebrate nerve cell, as 

 well as with that substance in invertebrates (McClure, Pfluge, 

 Lugaro, and others). This is shown by double staining with 

 methylen blue and eosin or erythrosin. Such methods show 

 the cell to be made up of two differently staining elements — 

 a varying number of irregular masses which stain with methy- 

 len blue, and a ground substance finely granulo-fibrillar or 

 homogeneous, which takes the red stain. This ground sub- 

 stance seems to be made up of two portions : a semi-fluid 

 (hyloplasm) and a granulo-fibrillar part. In general the blue- 

 staining substance may be said to be restricted to the more 

 peripheral parts of the cell. The masses vary much in size, 

 small granules as well as large masses being seen ; the former 

 existing nearer the center of the cell than the latter. In cells 

 containing an excentric invaginated nucleus the area opposite 

 the inpushing of the nuclear membrane is seen to be made up 

 of very fine granules which stain red. In such cells the chro- 

 mophilous masses were found disposed in the peripheral portion 

 of the cell, around the nucleus. 



