APPENDIX. 157 
separate again, then allowing the contents of the beaker to cool to 
7° C.; transferring to the weighed filter and washing with a little 
90 per cent. alcohol until the filtrate measures 25 cc. ; the filter with ~ 
contents is then at once transferred to the beaker, dried at 101° C, and 
weighed. To the weight of the benzoyl-eugenol must be added 0°550 
gm., the — — = oe ec, 90 _ cent, ne ohol; this weight 
multiplied by 16 nd diy ided by 268 
(the molecular a of Lenhaphseupennly wives the amount of 
eugenol in 5 gms, oil; for the percentage multiply again by twenty. 
An examination of sixteen samples showed the eugenol to vary 
from 70'87 per cent, to 90°64 per cent.; the oil distilled from the 
stems was found (contrary to expadbakions) to contain a high percent- 
age of eugenol, 83—85 per cent.; the specific gravity of the oil was 
not found to agree with the percentame of eugenol as the following 
show: 1:059=83°2 per cent.; 1065=80°89 per cent.; 1-065= 82°77 
per cent. ; 1:0615=84-10 percent. ; 1:0655 = 90°64 per cent. ;1°061= 
81°18; this led to the belief that there must be a third constituent 
present in the oil, for if there were only eugenol and sesqui-terpene 
the specific gravity should vary in accordance with the percentage of 
eugenol. (Pharm, Centralhaile, 1891, 589, Am. Journ. Pharm., 
Jan,, 1892.) 
PASSIFLOREZ, 
Carpaine, the alkaloid in the leaves of Carica Papaya. 
A new alkaloid has recently been detected in papaw leaves by 
M. Greshoff, of the Chemico-Pharmacological Laboratory at Buiten- 
zorg in Java. It was obtained by digesting the powdered leaves in 
spirit acidulated with acetic acid s removing the spirit by distillation, and 
with ether, and carbonate of soda was added until an al e reaction 
was evident. The precipitate thus obtained was readily soluble in 
ether, and on evaporation of the ether the “ carpaine ” was obtained 
in colourless rosettes of crystals to the extent of about 0°25 per cent. 
of the leaves employed. Although the freshly pecipitated alkaloid 
is readily soluble in ether, when once crystallized it redissolves but 
slowly, so that the crystals can be purified and rendered perfectly 
white by washing with a little ether, but the percentage obtained is 
thus reduced to 0°15 per cent, On a large scale the lime and 
