“APPENDIX, 1si 
leaves of the belladonna plant both contained principally hyoscya- 
mine, with small quantities of ready-formed atropine. As to t 
fruit, the unripe berries of the wild plant eentained chiefly. hyoscya- 
mine and a little atropine, but the ripe fruit contained only atropine. 
The ripe berries of cultivated plants, however, yielded both hyoscya- 
mine and atropine, while the ripe berries from var, lutea gave 
atropine and a small quantity of a base probably identieal with 
Hesse’s atropamine. Turning to other Solanaceous plants, fresh 
and old stramonitm seeds yielded chiefly hyoscyamine, together wit 
small quantities of already-formed atropine, and scopolamine. The 
‘Teaves of the potato plant (Solanum tuberosum), besides yielding 
betaine, gave indications of the presence of an oid having a 
mydriatic action, which seemed also to resemble a mydriatic base 
present in Solanum nigrum and Lyetum barbarum, The ‘aves of 
Nicotiana tabacum also yielded traces of a mydriatic alkaloid, and 
lastly the seed, herb, and root of Antsodus luridus all contained 
hyoscyamine only, (Pharm, Journ., Noy. 28, 1891.) 
Tobacco Smoke. 
Tobacco-smoke varies in character according to the proportion of 
air admitted during combustion, oxidation being necessarily more 
perfect in the case of a cigar than when the tobacco is smoked in a 
pipe. In the latter case,a portion of the condensible products is 
deposited in the liquid state. Tobacco-smoke consists in part of 
permanent gases, the proportions of carbon dioxide and carbon mono-e. 
oxide in which have been determined by G. Krause. Vohl found 
sulphuretted hydrogen and hydrocyanic acid, and from 0-7 to 2-8 
grammes of-ammonia for 100 of tobacco smoked. Vohl and Eulenberg 
(Arch. Pharm., {2}, exlvi., 130) experimented on the smoke of strong 
a s d 
through dilute sulphuric acid. The alkali absorbed cast dioxide, 
sulphuretted hydrogen, Spey bere —- acetic, proponic, butyric 
an 
d valeric aci of ca proic ie 
and succinic acids could not be_ eroceiatuad scnisbuctrety. The 
acid absorbed ammonia, pyridine, C°H°N, and all the homologues of 
the series to viridine, C'*H*°N, inclusive. In addition to the above, 
earbon monoxide, methane, and several hydrocarbons of the acetyl-— 
ene series were detected. Pyridine was the chief base in the mone 
