[nichoixs] blood sera IN TUBERCULOUS INFECTION 11 



Guinea-pig V. 



Killed April 15th. Inoculated in left leg. Slight haemorrhage in region 

 of original inoculation. The glands in the left inguinal region were enlarged 

 and reddened, and a few mesenteric glands were swollen. Smears from 

 mesenteric glands showed no tubercle bacilli. All organs normal. Cultures 

 from inguinal glands, heart-blood, and bile, sterile. 



Guinea-pig VI. 



Killed April 15th. Inoculated intraperitoneally. Moderate hsemorrhage 

 at site of inoculation of serum with a haematoma in the left inguinal region. 

 At site of original inoculation the abdominal wall was thickened and con- 

 tained a small caseous focus. All organs normal. Cultures heart-blood and 

 bile, sterile. Given sernm. 



Guinea-pig VII. 



Inoculated in left leg. Given serum. Great extravasation of blood into 

 tissues of the thorax and abdominal wall. Glands of left inguinal region and 

 one or two retroperitoneal glands on the left side enlarged, reddened, and 

 the latter with some spots of opaque white. Stomach and intestines reddened 

 and distended with gas. Other organs normal. Cultures from heart-blood 

 and retroperitoneal gland, sterile; from liver, staphylcoccus albus. 



Guinea-pig VIII. 



Died on eighteenth day. Inoculated in left leg. Given serum. Site of 

 serum injections in the abdominal wall infiltrated, reddened, and acutely 

 inflamed. There was one small superficial focus with necrosis. The tissues 

 over the thorax were much infiltrated. Spleen: swollen. Kidneys: congested 

 with petechial spots. Mesenteric glands: enlarged and red, but not caseous. 

 Cultures from mesenteric glands, sterile; from suprarenal, staphylococcus 

 albus. 



Rabbit I. 



Inoculated in leg. Given serum. No local signs at point of inoculation, 

 All organs absolutely normal. 



Rabbit II. 



Killed in about thirty days. Inoculated intraperitoneally. One mesen- 

 teric gland enlarged, not proved to be tuberculous. 



Rabbit III. 



Killed in about thirty days. No local signs at site of subcutaneous 

 inoculation in abdomen. All organs normal except the liver which contained 

 coccidia. A few mesenteric glands enlarged along the vessels as if from 

 haematogenic infection, but films from these showed no tubercle bacilli. 



Rabbit IV. 



Inoculated intraperitoneally. Killed May 12th. No local signs at site 

 o! inoculation. All organs healthy looking. One or two enlarged glands 

 noticed in the mesentery. Smears from these did not show tubercle bacilli. 



Rabbit V. 



Died in thirteen days. Inoculated in leg. Given serum. Abdominal 

 and thoracic walls thickened, reddened, and very œdematous. One or two 



