FAMILY II. CHLAMYDIACEAE 



965 



Ruska et al., loc. cit.; Rickettsiaformis muris 

 Zhdanov and Korenblit, Jour. Microbiol., 

 Epidemiol, and Immunobiol. (Russian), No. 

 9, 1950; Chlainydozoon murinus Ryzhkov, 

 Voprosy Meditsinskoi Virusologii (Prob- 

 lems of Medical Virology), Akad. Med. 

 Nauk, S.S.S.R., Moskau, 3, 1950, 17.) 



bron.cho.pneu.mo'ni.ae. Gr. noun bron- 

 chus trachea, bronchus; Gr. noun pneumonia 

 pneumonia; M.L. noun bronchopneumonia 

 bronchopneumonia; M.L. gen. noun broncho- 

 pneumoniae of bronchopneumonia. 



Coccoid cells resemble those of Miyagawa- 

 nella pneumoniae. 



Cultivation: Same as for Miyagaivanella 

 lymphogranulomatosis . Does not grow in the 

 allantoic cavity of the chick. 



Immunology: Same as for M. lympho- 

 granulomatosis, but no soluble antigen has 

 been demonstrated. 



Toxic factor: High concentrations of this 

 agent in heavily infected yolk sacs and in 

 yolk injected intravenously are verj' rapidly 

 fatal to mice. 



Pathogenic for mice, hamsters and fer- 

 rets. Produces a moderately severe pneumo- 

 nitis. 



Tissue tropism: Shows a predilection for 

 the lungs. In mice, it is also infective by the 

 intravenous route. 



Antibiotic- and chemo-therapy: Suscep- 

 tible to sulfonamides and to antibiotics. 



Source: Found in the lungs of certain 

 stocks of the laboratory mouse. 



Habitat: The etiological agent of mouse 

 pneumonitis. 



6. Miyagawanella felis Rake, 1948. 

 (Rake, in Manual, 6th ed., 1948, 1118 

 Ehrlichia felis Krassilnikov, Guide to the 

 Bacteria and Actinomycetes, Izd. Akad 

 Nauk, U.S.S.R., Moskau, 1949, 7i3;Rickett 

 siaformis felis Zhdanov and Korenblit 

 Jour. Microbiol., Epidemiol, and Immuno 

 biol. (Russian), No. 9, 1950, 43; Chlamydo- 

 zoon felis Ryzhkov, Voprosy Meditsinskoi 

 Virusologii (Proli. Mod. Virol.), Akad. Med 

 Nauk, S.S.S.R., Mo.skau, 3, 1950, 17; Miya 

 gawanella felinis Sprockhoff, Deutsch 

 Tierarztl. Wochnschr., S3-U, 1953, 256.) 



fe'lis. L. noun felis the cat. 



Coccoid cells resemble those of Miyagawa 

 nella lymphogranulomatosis. 



Cultivation: Same as for Miyagawanella 

 psittaci. 



Immunology': Same as for M. psittaci, but 

 nothing is known about inapparent infec- 

 tions in the natural host, the domestic cat. 



Toxic factor: Infected yolk sac or other 

 membranes and yolk or other fluids are rap- 

 idly fatal when injected intravenously into 

 mice or chicken embryos or intraperiton- 

 eally into mice. 



Pathogenic for cats, hamsters, mice and 

 chicken embryos. Causes a fatal pneumo- 

 nitis with acute conjunctivitis in cats. 



Tissue tropism: Shows a predilection for 

 the lungs and for the conjunctivae. In lab- 

 oratory rodents this species is infective by 

 the intranasal, intraperitoneal, intracere- 

 bral and intravenous routes. 



Antibiotic- and chemo-therapy: Same as 

 for Miyagawanella ornithosis. 



Source: From the lungs of infected cats. 



Habitat: The etiological agent of one 

 form of cat nasal catarrh, influenza or dis- 

 temper (Baker, Science, 96, 1942, 475) and 

 feline pneumonitis. 



7. Miyagawanella louisianae Rake, 

 1948. (Rake, in Manual, 6th ed., 1948, 1118; 

 Ehrlichia lousianae (sic) Krassilnikov, 

 Guide to the Bacteria and Actinomycetes, 

 Izd. Akad. Nauk, U.S.S.R., Moskau, 1949, 

 743.) 



lou.i.si.a'nae. M.L. noun Louisiana the 

 state Louisiana; M.L. gen. noun louisianae 

 of Louisiana. 



Coccoid cells resemble those of Miyaga- 

 wanella psittaci. 



Filterability: Passes through Berkefeld N 

 and Mandler 6, 7 and 9 filters. 



Cultivation : Grows in the yolk sac of the 

 chicken embryo. 



Immunology : Indistinguishable from 

 other miyagawanellae by complement-fixa- 

 tion tests with yolk-sac antigens. Partly 

 distinguished from Miyagawanella psittaci 

 and M. ornithosis by active immunization 

 in mice and guinea pigs. 



Pathogenic for man, guinea pigs, cotton 

 rats, mice and chicken embryos. Slightly 

 pathogenic for white rats, golden hamsters 

 and deer mice. Monkeys {Macacus rhesus), 

 rabbits, muskrats and nutria are unaffected. 



