966 



ORDER I. RICKETTSIALES 



Causes a highly fatal pneumonitis and sep- 

 ticemia in man. 



Tissue tropism: Causes a septicemia. In 

 man this species shows predilection for the 

 respiratory tract. In laboratory rodents it 

 is infective by the intranasal, intraperito- 

 neal, intracerebral, intramuscular and sub- 

 cutaneous routes. 



Antibiotic- and chemo-therapy: Same as 

 for Miyagawanella ornithosis. 



Source: From the sputa and organs of in- 

 fected persons. 



Habitat: The etiological agent of Louis- 

 iana pneumonitis (Olson and Larson, U. S. 

 Pub. Health Repts., 59, 1944, 1373); the so- 

 called Borg strain. 



8. Miyagawanella illinii Rake, 1948. 

 (The Illinois virus, Zichis and Shaughnessy, 

 Science, 102, 1945, 301; Rake, in Manual, 6th 

 ed., 1948, 1119; Ehrlichia illinii Krassil- 

 nikov. Guide to the Bacteria and Actino- 

 mycetes, Izd. Akad. Nauk, U.S.S.R., Mos- 

 kau, 1949, 743.) 



il.li'ni.i. Fr. noun Illinois a place name; 

 M.L. gen. noun illinii (probably intended 

 to mean) of Illinois. 



Coccoid cells resemble those of Miyaga- 

 ivanella lymphogranulomatosis . 



Filterability: Passes through Berkefeld N 

 and W filters. 



Cultivation: Grows in the yolk sac of the 

 chicken embryo. 



Immunology: Distinguished from other 

 miyagawanellae by neutralization tests in 

 mice with chicken antisera and partly from 

 Miyagawanella psittaci, M. ornithosis and M. 

 pneumoniae by active immunization in mice. 



Pathogenic for man and for white mice. 

 Causes a highly fatal pneumonitis in man. 



Tissue tropism: Infective in mice by the 

 intranasal, intraperitoneal, intracerebral 

 and subcutaneous routes. 



Source: From the lungs of infected per- 

 sons. 



Habitat: The etiological agent of a highly 

 fatal pneumonitis in man. 



9. Miyagawanella opossunii (Ryzhkov, 

 1950) Rake, comb. nov. (Opossum virus A, 

 Roca-Garcia, Jour. Inf. Dis., 85, 1949, 275; 

 Chlamydozoon opossumi Ryzhkov, Voprosy 

 Meditsinskoi Virusologii (Prob. Med. 



Virol.), Akad. Med. Nauk, S.S.S.R., Mos- 

 kau, 3, 1950, 17; Rickettsiajormis opposum 

 (sic) Zhdanov, Opredelitel Virusov Celov- 

 ska i Zivotmych, Izd. Akad. Med. Nauk, 

 U.S.S.R., Moskau, 1953, 185.) 



o.pos'su.mi. Am.Ind. noun opossum the 

 opossum, a North and South American mar- 

 supial; M.L. gen. noun opossumi of the opos- 

 sum. 



Coccoid cells resemble those of Miyaga- 

 wanella lymphogranulomatosis. Non-motile. 

 Stain red-purple with Giemsa's or Wright's 

 stain, and red with Macchiavello's and blue 

 with Castaneda's stain. Gram-negative. 



Filterability: Passes through a Berkefeld 

 V but not an N or a Seitz filter. 



Cultivation: Grows in tissue cultures of 

 mouse or chicken cells and in the yolk sac 

 of the chicken embrj^o. 



Immunology: Contains a group comple- 

 ment-fixing antigen in common with the 

 other mij^agawanellae. Shows a serological 

 relationship to M. pneumoniae by cross- 

 protection tests. 



Toxic factor: Same as for M. lymphogran- 

 ulomatosis. 



Pathogenic for South American opossums, 

 producing a central-nervous-system disease 

 and a paralysis of the hind quarters. Patho- 

 genic for mice and chicken embryos. Not 

 pathogenic for pigeons or guinea pigs. 



Tissue tropism: Infects opossums in the 

 laboratory by the intraperitoneal but not 

 by the subcutaneous route. Infects mice by 

 the intracerebral or the intranasal but not 

 by the intraperitoneal route. 



Chemotherapy: Not susceptible to sulfon- 

 amides. 



Source : Isolated from an opossum (Didel- 

 phys paraguayensis) trapped in a district of 

 the municipality of Cdqueza, State of Cun- 

 dinamarca, Colombia. 



Habitat: The etiological agent of paral- 

 ysis in opossums. 



10. Miyagawanella ovis (Zhdanov, 1953) 

 Rake, comb. nov. (Minute organisms from 

 enzootic abortion of ewes. Stamp, IMcEwen, 

 Watt and Nisbet, Vet. Record, 62, 1950, 251; 

 Virus of ovine enzootic abortion. Stamp, 

 Jour. Comp. Path, and Therap., 61, 1951, 

 215; also see Monsur and Barwell, Brit. 

 Jour. Exp. Path., 32, 1951, 414; Rickettsia- 



