FAMILY III. BARTONELLACEAE 



979 



Source and habitat : Found in the blood of 

 the gray-backed deer mouse (Peromysciis 

 mnniculatiis gracilis) . 



3. Eperythrozoon dispar Brujnoghe 

 and Vassiliadis, 1929. (Ann. de Parasitol., 

 7 1929, 353.) 



dis'par. L. adj. dispar unlike. 



Resembles Eperythrozoon coccoides in 

 staining, in distribution on the erythrocytes 

 and also in appearance, except that circular 

 discs with solid staining centers may greatly 

 outnumber the ring forms. Found on the red 

 blood cells and in the plasma. Size range 

 similar to that of Eperythrozoon coccoides; 

 there are also some larger ring forms. 



Has not been cultivated. 



Immunology: Infection is followed by 

 premunition, and latent infection is made 

 manifest by splenectomy. Splenectomized 

 rabbits premunized against E. coccoides do 

 not react to inoculation with E. dispar; if 

 the latter is injected first, the rabbits do 

 not react to E. coccoides. 



Inf ectivity : Infective for the European 

 vole (Arvicola (Microtus) arvalis), the Amer- 

 ican vole {Microtus pennsylvanicus pennsyl- 

 vanicus), the dwarf mouse {Mus minutus), 

 the rabbit and Mus acomys. Not infective 

 for albino rats or albino mice. 



Source: Recovered from the blood of in- 

 fected animals. 



4. Eperythrozoon wenjonii Adler and 

 Ellenbogen, 1934. (Jour. Comp. Path, and 

 Therap., 47, 1934 (Sept. 3), 220.) 



wen.yo'ni.i. M.L. gen. noun wenyonii of 

 Wenyon; named for Dr. C. M. Wenyon, who 

 studied these organisms. 



Morphologically similar to Eperythrozoon 

 coccoides. Coccoid and often vesicular, 

 staining pale red with Giemsa's stain and 

 varying from 0.2 to 1.5 microns in diameter. 

 Multiplication seems to be by budding, by 

 fission and by filamentous growths from the 

 ring forms. Up to 50 or 60 organisms are 

 found on one red blood cell. These are ar- 

 ranged in irregular chains or in tightly 

 packed groups. 



Cultivation: Not reported. 



Immunology: The organism creates a 

 state of premunition; latent infection is 

 made manifest by splenectomy. 



Pathogenicity: Cattle are susceptible, but 

 sheep are not infected either before or after 

 splenectomy; a splenectomized pig proved 

 non-susceptible. 



Source: Recovered from the blood of in- 

 fected cattle. 



Habitat: Found in the blood of infected 

 cattle; arthropod transmission has not been 

 proved. 



5. Eperythrozoon ovis Neitz et al., 

 1934. (Neitz, Alexander and du Toit, Ad- 

 dress, Biological Society, Pretoria, Mar. 15, 

 1934; from Neitz, Onderstepoort Jour. Vet. 

 Sci. and Anim. Ind., 9, 1937, 9.) 



o'vis. L. noun ovis a sheep. 



Delicate rings approximately 0.5 to 1.0 

 micron in diameter, though occasionally 

 larger. In addition there are triangular 

 forms with rounded angles as well as ovoid, 

 comma, rod, dumbbell and tennis-racket 

 forms. Found supra-cellularly on the eryth- 

 rocytes, but often free. Colored pale purple 

 to pinkish purple with Giemsa's stain. Sug- 

 gested mode of multiplication is by budding. 



Has not been cultivated. 



Immunology: The immunological state in 

 sheep appears to be that of the premunition 

 type. 



Pathogenicity: Sheep, antelopes and 

 probably goats and splenectomized calves 

 are susceptible. Dogs, rabbits and guinea 

 pigs are refractory, and a splenectomized 

 pig was not infected. The distinctive feature 

 of Eperythrozoon ovis is its ability to provoke 

 illness in normal animals without resorting 

 to splenectomy. 



Source: Found in the blood of infected 

 sheep in South Africa and in the United 

 States. 



Habitat: Occurs in the blood of infected 

 animals. No ectoparasites found on sheep 

 were naturally infected, but an arthropod 

 is suspected as a vector. 



6. Eperythrozoon suis Splitter, 1950. 

 (Science, HI, 1950, 513.) 



su'is. L. noun sus, suis a pig. 



Rods, rings, coccoids and various budding 

 forms have been reported, a ring form aver- 

 aging 0.8 to 1.0 micron in diameter being the 

 most common. Larger ring and discoid types 



