[PARSONS-VINCENT] THE BLOOD-PRESSURE CURVE \M 



A slighter dip is obtained when the lumbar method is adopted. 

 V. Anrep used A. C. E. mixture and morphia. Chloroform, curare 

 and morphia modify the curve so that there is little or no dip, only 

 a "step" on the rise. 



In many of our tracings the "step" and the subsequent "dip" 

 are quite distinct, and the augmentation of the heart is very manifest. 

 Ligature of the veins of one gland does not always abolish these 

 secondary effects on the same side and strange to say, thorough 

 cauterising of the medulla of the gland often leaves the curve practi- 

 cally unchanged. Extirpation of both adrenal bodies abolishes 

 the "step" and the augmentation of the heart, but leaves a certain 

 dip in the tracing. We are inclined to conclude provisionally that the 

 greater part of the dip and the whole of the previous "step" and 

 augmentation of the heart are due to adrenin poured into the circula- 

 tion as a result of the splanchnic stimulation, but that a part of the 

 fall or dip is a true vaso-motor reaction. 



Injection of a one per cent solution of nicotine into the medulla 

 of the gland abolishes the "step" and a greater part of the "dip," 

 as well as the augmentation of the heart. 



