[NICHOLLS] CALCIUM CONTENT OF THE BLOOD 89 
(3). In acromegaly, a disease due to some disorder of the pituitary, 
the thyroid has been found enlarged, cystic, or atrophic, and in some 
cases symptoms of myxcedema or exophthalmic goitre have developed. 
(4). Extracts of the pituitary (infundibular portion) increase blood 
pressure; extracts of the thyroid lower it. 



THYROID 
GLAND 
SOMATIC 
DEVELOPMENT, 





OVARIES 
TESTES 
PITUITARY 
BODY 

Relationships between the pituitary and the sexual organs and func- 
tions :— 
(1). Tumours of the pituitary are known to be associated with 
hypoplasia of the genital organs, and lack of sexual power, both in the 
male and in the female. 
(2). In giantism and acromegaly, diseases associated with gross 
disturbance of the pituitary function, genital hypoplasia and functional 
inadequacy have been observed. 
(3). During pregnancy, and apparently in consequence of it, the 
pituitary enlarges, and shows hyperplasia of what are called the “ Haupt- 
zellen. ” 
(4). Extracts of the infundibular portion of the pituitary excite 
powerful contractions in the pregnant uterus. 
Sec. LV, 1910.16: 
