0.— NOTE OX thp: co-relatiox of several dis- 

 eases OCCUKKINCi AMONG ANIMALS IN SOUTH 

 AFRICA. 



Bv Ar.KXAXDKu Edingtox, i\I.D., F.R.S.E., Dikkctok of thk 

 Colonial Bactkkiological Ixstitutk, Capk Coloxv. 



Ill South Africa one finds quite a number of ailments occurring 

 in tile domesticated animals and, while the onset, symptoms and 

 morbid anatomy of those affected shew the ailments to be peculiar 

 to Africa, the names j^iven to the maladies are unknown in any other 

 country. 



Horses and mules are liable to the enormously fatal malad\ 

 known as Horse-sickness. 



The mode (if onset, symptoms and morbid anatom\ of this 

 disease have been already fully described.* 



High-bred goats and .sheep are exceedingly liable, in certain 

 areas of (^ape Colony, to a disease known as Heart-water. The 

 areas within which this disea.se exists begin at the coast in the 

 Eastern Province and extend inland irregularly for some distance. 



In the animals which die of this disease it is common to find 

 a considerable quantity of pale yellow serous effusion in the 

 pericardium. 



The epi, m\<) and endocardium commonlv shew little or no 

 departure from the normal. 



The pleural I'avitv mav contain some vellow serous fluid or ma\ 

 be empty. 



The lungs mav be almost normal or there mav be some exudation 

 found into the inlerlobuiar tissue. 



While the lungs as a whole may be quite pale in colour there 

 may be found irregular sharply defined chocolate-coloured patches of 

 congestion. 



There may also be found more or less of gastroenteritis and. in 

 cases running to the full term, the gall bladder may be distended with 

 more or less in.spi.ssated bile which, while usually of a deep bottle 

 green, may be sometimes brown in colour. 



The incubation period after the intravenous inoculation of a 

 clean goat with 5 c.c. to 30 c.c. of the blood of an animal dying of 

 the malady is as a rule about ten days. This period, however, may 

 be greatly diminished or extended ; from a few days up to nearly 

 three weeks in some cases. 



From the point of view of experimental infection the results, 

 which I have obtained from experiments conducted on nearly five 

 hundred goals, are paradoxical in the extreme. 



VVhen 1 first liegan my investigations I u.sed goals which were 

 born and reared on a farm, near Grahamstown. which was believed 

 to be outside of the area infested with the disease. 



Vide reports of the Director of the Bacteriological Institute, 



