VENOM INJECTED INTO THE MUSCLES. 509 
with Puff Adder venom under the skin, the muscles were not 
affected at all, and there was no hemorrhage in any of the organs 
or into the body cavities. The only hemorrhage which occurred 
was between the skin and the muscles of the thigh which had 
been injected. In some cases the hemorrhage could be traced 
to the top of the thigh and a little way up the side. Even in 
those fowls which were injected with four drops of venom, and 
which subsequently died, there was a total absence of hemorrhage 
into the muscles of the injected part, or of other parts of the body. 
This cannot be attributed to the fowls dying too rapidly, or the 
full effect of the hemorrhagin principle of the venom to exert 
a toxic influence, for the majority survived from twelve hours to 
three and even four days. 
VENOM INJECTED INTO THE MUSCLES. 
A number of fowls were taken, and into the thigh of each 
three drops of Puff Adder venom, mixed with a teaspoonful of 
pure water, was injected deep into the muscular tissue. Some 
of the fowls died in two hours, and none survived more than 
four and a half hours. In all cases from the first five minutes 
after injection till death, the fowls moped, but were not insensible 
till the last five minutes of life. Several other fowls were injected, 
each with two drops of venom mixed with a little pure water. 
The fowls all died within seven hours. Most of them were dead 
in four hours. 
In the post-mortem on those which were injected with three 
drops of venom, severe hemorrhage was seen to have taken place 
into the muscles of the injected leg, as well as up the side and into 
the body cavities. The muscles of the leg were saturated with 
blood which had oozed through the walls of the vessels, and 
presented a soft, pulpy horrible appearance, as is the case when 
the Puff Adder inflicts a normal bite into the muscles of its victim. 
In those which were injected with two drops of venom, the 
hemorrhage, although extensive, both in the muscular tissue 
and under the skin, was not so great, owing to the lesser quantity 
of venom. 
CONCLUSIONS. 
These experiments go to show that Puff Adder venom if 
injected just under the skin, and not into the muscular tissue, is 
