126 CM. JACKSON AND C. A. STEWART 



SUMMARY 



1. Albino rats fully refed after underfeeding from birth to 

 three, six, or ten weeks, or from three weeks to nearly a year of 

 age, grow variably, but usually fail to reach the normal adult 

 size. The ultimate effect varies according to the length of the 

 underfeeding period, the age at which the inanition occurred, the 

 sex (body weight more affected in males), the severity and the 

 character of the inanition. 



2. In the test rats refed to maximum body weight, the body 

 length and tail length appear slightly subnormal, head, limbs, 

 and trunk nearly normal in weight; skeleton, integument, and 

 musculature usually slightly subnormal, visceral group slightly 

 above normal, and 'remainder' variable. 



3. Of the individual organs, the brain, spinal cord, hypophysis, 

 and lungs of the test rats average slightly subnormal in weight, 

 the ovaries very markedly so. The atrophy of the ovaries prob- 

 ably accounts for the reduction of reproductive capacity in the 

 test females, which is especially marked after the long under- 

 feeding periods. The heart and alimentary tract appear slightly, 

 and the testes and epididymides very definitely, above normal 

 weight. The other organs appear either normal or irregular in 

 weight, in comparison with normal controls of the same body 

 weight. 



4. While some abnormalities thus occur in the test rats, they 

 are usually slight, and in general it may be said that the organs 

 and parts are nearly normally proportioned in the permanently 

 stunted rats. Thus the earlier starvation apparently retards or 

 inhibits the later growth process of the body as a whole, with 

 the few exceptions above noted. 



