164 Oscar Riddle 



of inheritance involved in the transmission of this anihne dye have 

 attracted an amount of attention which make a fuller treatment 



necessary.^ 



It is important that any statement concerning the inheritance 

 of this or another pigment be accompanied by a statement 

 of the facts concerning the behavior of this substance in 

 metabolism. That is to say, if we make statements concerning 

 the passage of a substance through follicular cells and of its 

 deposit, distribution, behavior or development within germ cells 

 and in their derivatives, it is obviously important to keep in view 

 what we know regarding the way this substance passes through 

 other membranes; how it exists, is distributed, behaves or develops 

 in somatic cells. It is of value to realize Aou- these things happen 

 in any membrane or cell of the body, because it is this same how, 

 or in other words, the mechanism of such successive transforma- 

 tions in the germ, that is the very self of inheritance. Again, if 

 we state our results on inheritance in terms of metabolism we are, 

 in this case at least, less liable to exaggerate the importance of our 



' Curing the two years since this paper was prepared and read other workers have under- 

 taken and reported work along similar or related lines; and quite recently, within four months, 

 three papers have appeared which make it seem advisable to divide this paper into two parts, 

 and to publish in full without further delay the part most intimately connected with the present 

 title. One is the more readily persuaded to this division and immediate publication because of 

 a communication which appeared in Science, September, 1909. Tr. Ludwig Sitowski there directs 

 attention to the fact that he had secured the deposit of Sudan III in the eggs of moths, and had 

 published an account of his experiments as early as 1905, but that his paper has been over- 

 looked until now by the writer and apparently by others. With pleasure the writer hastens to 

 make acknowledgment of his excellent work. Only the timely appearance of his communication 

 together with the fortunate circumstance of delay in the publication of this article have made it possible 

 to give his work the credit it deserves. It is hoped that Cr. Sitowski will realize that the place 

 and title of his publication were such as to make it not difScult for American workers to oserlook. 



Sitowski evidently has not seen even the abstract of the writer's paper but only a short 

 notice or review of it which was written by H. A. in the Zeitschrift f. d. .Ausbau der Entwick- 

 lungslehre, Bd. Ill, Heft 2, 1909. 



The writer's report of this work has received notice in several quarters, and in almost 

 every instance he has been credited with the works of others, or to others has been attributed 

 work done by him. In these shiftings he usually has fared better than he deserves; but it 

 seems that the results thus far obtained in this field should be brought together in such a way that 

 it may be made plain just what has been done and incidentally who did the work. It is partly 

 for these reasons that the entire literature on Sudan, so far as the writer has 'neen able to find it, is 

 here brouelit togetlier and an outline of the results given. 



