Bedford, Olfactory Nerve in Sivine. 391 



much modified. Up to very recent time, there has been con- 

 fusion, even among writers of the highest merit. 



Hertwig,^ as late as 1892, says: "Finally in treating of 

 the development of the cerebrum, there is still to be considered 

 an appendage of it, the olfactory nerve. This part as well as 

 the optic nerve is distinguished from the peripheral nerves by 

 its entire development and must be considered as a specially 

 modified portion of the cerebral vesicle. The older designation 

 of nerve, therefore, is now more frequently replaced by the 

 more appropriate name of olfactory lobe." Hertwig then goes 

 on to describe the development of the lobe of man, completely 

 ignoring the development of the fibers which form the 

 real olfactory nerve. The true condition is made clear by Ed- 

 iNGER.^ "From the epithelium of the nasal mucous membrane 

 long terminal fibrillae run backward. They are called fila olfac- 

 toria and pass through the cribiform plate into the cranial cavity. 

 .... The fila olfactoria pass to an anteriorly directed evagina- 

 tion of the fore-brain vesicle. This evagination forms on the 

 base of the brain a more or less elongated tube which, in most 

 animals, remains hollow, tractus and bulbus olfactorius." 

 Further he says that the tractus, which connects the bulbus 

 with the remaining portion of the brain, in some animals, might 

 easily be taken for the olfactory nerve, which, however, termi- 

 nates at the olfactory bulbus. 



Lee,^ Locy^ and others have directed attention to the true 

 relation of the fila olfactoria and the tractus. It is with the 

 development of these fila olfactoria that this paper is con- 

 cerned. 



' Oscar Hertwig. Text-Book of the Embryology of Man and Mammals. 

 Translation by Edward L. Mark, pp. 448-449. 



2 Edinger. Hall's Translation, p. 146. 



^ Lee. Zur Kentniss des Olfactorius, Berichte Naturf, Gesellsch. Freiburg, 

 Bd. VII, 1S93. 



* Wm. a. Locy. New Facts Regarding the Development of the Olfactory 

 Nerve, Anat. Anz., XVI, pp. 273-290. 



