220 E. A. BAUMGARTNER 



Herring ('13) briefly described the histological features in adult 

 Testudo graeca and Lacerta viridis. He recognized an epithelial 

 lobe, separated caudally from a pars intermedia. The epithelial 

 lobe has an acinous, or cord like arrangement of cuboidal or 

 columnar cells, most of which are clear, others deeply granular. 

 The latter frequently form solid columns, while the clear cells 

 surround a lumen containing a stainable colloid. This portion 

 is very vascular. The pars intermedia is a solid band of clear 

 epithelial cells lying at the base of the brain and covering the 

 anterior end of the glandular part. The cells of the pars inter- 

 media are arranged in columns, or occasionally, as acini con- 

 taining colloid, and form several layers at the base of the brain. 

 Caudally, they form a single layer of columnar cells. Herring 

 believes the colloid is stored secretion. 



Sauerbeck ('05) in describing the hypophysis of a Sphenodon 

 embryo with a malformed brain, briefly stated that the hypo- 

 physis was made up of scattered epithelial cells, arranged in 

 cords extending from the abnormally high infundibulum to the 

 pharyngeal roof. The malformed condition of the brain was 

 probably responsible for the elongated hypophysis. 



Viguier ('11) studied the histological appearance of the hy- 

 pophysis of the lizard, Uromastix acanthinurus, after thyreoid- 

 ectomy. Normally, the hypophysis is formed of epithelial cords 

 surrounded by some connective tissue and capillaries. Clear 

 and vacuolated and darkly-granular cells form acini with walls 

 two or three cells deep, the central layer being flattened about 

 a lumen. Eight or ten weeks after thyreoidectomy, cells with 

 basophilic granules, and others staining deeply with picric acid 

 are present. Peripheral acidophilic cells surround the capillaries 

 and may contain dark-staining granules. The nuclei are large 

 and contain nucleoli. The capillaries are greatly dilated and 

 congested. 



The kinds of cells present, and their arrangement and rela- 

 tions, have been variously described. The lack of comparison 

 of the structure and histogenesis of the hypophysis is apparent 

 from this review of the literature. As various names have been 

 applied to the parts of the adult reptilian hypophysis, a table 



