THE HYPOPHYSIS IN REPTILES 245 



growth in the hypophysis, or at least of this part, during adult 

 life. Increase of glandular growth during adult life in Acanthias 

 has also been noted. The band-like proximal portions of the 

 lateral buds curve backward around the sides of the anterior 

 lobe to near its caudal end. 



In a median sagittal section of a 3 mm. lizard embryo there 

 is a well marked hypophyseal angle. In the next embryo de- 

 scribed Rathke's pouch and the lateral buds are well developed, 

 the latter being separated from Rathke's pouch by wide venous 

 sinuses as described by Gaupp ('93). In 15 mm. Lacerta agilis 

 embryos the lateral buds appear as two small, blunt evaginations. 

 Their later history in Lacerta agilis could not be followed. 

 However, in a transversely sectioned series of Lacerta muralis, 

 28 mm. long (total length, H. E. C. 809) the lateral buds are 

 closely applied to the floor of the brain on either side of Rathke's 

 pouch. In a specimen of Lacerta viridis 37 mm. in length, two 

 masses of cells, apparently the lateral buds, are imbedded in 

 the meninges and are completely isolated from the hypophysis. 

 It can not be said that these masses are degenerating. In a 

 limited series of Hemidactylus adults, such masses of cells were 

 not observed and in adult Sceloporus they are entirely absent. 

 In Lacerta ocellata, agilis and muralis, Haller ('96) and Gisi 

 ('07) found nothing corresponding to a pars tuberalis, although 

 Gisi described a 'pars terminalis' in Chamaeleon. In late Lacerta 

 embryos Gaupp found that the lateral buds become isolated 

 masses imbedded in the meninges. Staderini ('03) and Bruni 

 ('14) described a similar development in Gongylus embryos. 

 Later ('05) Staderini described isolated masses imbedded in the 

 brain of adult Gongylus although Orru ('00) does not mention 

 them in either embryos or adults of this form. It appears then 

 that the lateral buds persist only in Gongylus, Chamaeleon, 

 and possibly in Lacerta, although the latter needs confirma- 

 tion. Stendell ('14) stated that the tip of the anterior lobe in 

 Lacerta vivipara forms the 'zungenformigen Fortsatz.' This 

 does not agree with my observations on the development of the 

 pars tuberalis in alligators and turtles or with those of Gisi ('07, 

 Sphenodon) and Tilney ('13, cat, bird). 



