44 H. HAYS BULLARD 



Both true interstitial granules and fat droplets are of wide dis- 

 tribution in striated muscle, occurring under normal physiological 

 conditions both in insect .muscle, and also in the skeletal and 

 cardiac muscle of vertebrates. 



The physiological significance of the true interstitial granules 

 is uncertain. 



The quantity of fat in muscle fibers is increased when the 

 animal (rat) is fed on fat meat and decreased during inanition. 

 The fat droplets of muscle fibers are reserved food material. 

 This conclusion was reached by Bell. 



This study was conducted under the direction of Prof. Irving 

 Hardesty and I am under obligation to him for many helpful 

 suggestions. I am also indebted to Prof. Gustav Mann who has 

 given me valuable assistance. 



LITERATURE CITED 



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Gesellschaft, Bd. 5. 



1903a tjber triibe Schwellung und Fettdegeneration. 



Deutsche path. Gesellschaft, Bd. 6. 



1903b tJber die Bedeutung myelinogener Substanzen im Zelleben. 



Deutsche path. Gesellschaft, Bd. 6. 

 Altmann, R. 1894 Die Elementarorganisrrien. 

 Arnold, J. 1900 tlber vitale Granulafjirbung in den Knorpelzellen, Muskel- 



fasern und Ganglienzellen. Arch. f. mikr. Anat., Bd. 55. 



1909a Zur Morphologie des Muskelglycogens und Zur Struktur der 



quergestreiften Muskelfaser. Arch. f. mikr. Anat., Bd. 73. 



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1911 The interstitial granules of striated muscle and their relation 

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