220 FRANKLIN PARADISE JOHNSON 



Enlarged glands and gland cysts 



In an embryo of 140 nnn. the epithelial tube of the caecum 

 is 1.4 mm. in diameter, and its villi 0.18 mm. to 0.27 mm. high. 

 For the most part the glands are 0.09 to 0.13 mm. in length and 

 0.054 to 0.072 mm. in width. Some of the glands, however, 

 are swollen at their lower ends, being from 0.09 mm. to 0.13 

 mm. in diameter. They are all supplied wdth lumina, which 

 in the enlarged glands are occluded at the necks of the glands. 

 More distally, the base of the vermiform process has a diameter 

 of only 0.9 mm. The villi are similar to those of the caecum, 

 and the bulbous glands are more numerous. Still more distally, 

 near the tip of the vermiform process, the villi are shorter (0.14 

 to 0.16 mm.), and the enlarged glands are found in still greater 

 numbers. Figure 27, from a model of the epithelium of the tip 

 shows some of these glands. Many have enlarged ends con- 

 nected with the surface epithelium by constricted necks. The 

 gland marked in the figure is the only gland which could be 

 found which is entirely cut off from the surface epithelium. 

 From serial sections, it is possible to make out that although 

 the bulb-like expansions are provided with decidedly large lumina, 

 these are totally cut off from the lumen of the vermiform process. 

 Moreover, the cells of the necks of the glands appear to be under- 

 going degenerative changes. In many places only a slight 

 strand of tissue, largely composed of epithelial cell nuclei, could 

 be found connecting the bulb with the surface epithelium. 



In the vermiform process of an embryo of 170 imn. the en- 

 larged glands are very numerous. Owing, however, to poor 

 preservation it is impossible to state whether they are connected 

 with the surface or not. In the connective tissue of the sub- 

 mucosa can now be seen distinct nodules of lymphoid tissue. 



Sections through the base of the vermiform process of an 

 embryo of 190 mm. shows ill-marked villi, 0.07 to 0.11 mm. in 

 height and of variable width. The glands, now 0.11 mm. to 

 0.16 mm. long, are more regular and only a few tend to be bulb- 

 ous. The condition found is quite similar to that of the sigmoid 

 colon of the same embryo with the difference that there are 



