348 Effa Funk Muhse. 



tr,ansitional gland (Fig. 40) from one animal presented conditions 

 similar to those found in the periphery of adjacent mature glands. 

 The cells in the lower two thirds of this gland were greatly enlarged 

 and very irregular, those of the upper part remained cubical. Many 

 of the large cells appear vacuolated, as is true of the periphery of 

 the mature glands of this individual. The secretion in the lumen 

 and the cyptoplasm of part of the cells is identical with that found at 

 the edge of the lumen of the mature glands. Further, certain parts 

 of this gland showed granules, similar to those of the mature secre- 

 tion. 



(h) The last stage preceding the mature resembles the preceding 

 in size and shape. There are no epithelial cells, but the lumen which 

 is almost filled with secretion is lined by naked nuclei (Fig. 41). 

 Such glands are really but small mature glands. A mature gland, 

 occurring elsewhere than in a wart, is very similar to this stage in the 

 parotids. 



A network of blood vessels has not been observed about the acinus 

 of a small gland, but the glands are in close association with the 

 lymph spaces of the outer loose cutis stratum. 



Degenerate forms. The developmental stages above described 

 precede the mature type. It, in turn, is followed by different degrees 

 of degeneration. Certain sacs, situated among the inner battery of 

 glands, are in a completely collapsed condition. All of the secretion 

 or the greater part is missing. The gland wall is greatly thickened, 

 but, except for contraction, the elements appear normal when com- 

 pared with those of the filled glands of the same region (Figs. 24, 

 53). The gland proper has dravra away from the network of capil- 

 laries, which have somewhat crowded together. A further degree 

 of degeneration is shown by collapsed glands, in which the normal 

 structure of the parts is no longer preserved. The walls are not con- 

 tinuous, blood corpuscles are scattered about in the gland area, 

 and a general breakdown is apparent (Figs. 23, 57, 58). The neck 

 and collar are also in a very degenerate condition. 



One Kind of Cutaneous Gland — Its Purpose and History. 

 Purpose. Wright ('84) figures and describes in the epidermis 



