522 



EDWARD B. MEIGS 



inWEIQtIT 

 60 r 



to 



20 

 10 

 



10 



I 2 3 

 H0UR5 



10 II a 1} 



If it> ir li 



Fig. 12 Changes in weight undergone by the sartorius (broken line) and stom- 

 ach muscle (unbroken line) of a frog 'in 2.3 per cent alanin solution. See Experi- 

 ments 45 and 46. 



10, 11 and 12 and Experiments 15, 25, 46, 76 and 79). Experi- 

 ments 14, 45, 75 and 78 show the behavior of the striated muscle 

 from the same frogs in the same solutions. The smooth muscle 

 remains alive in these solutions decidedly longer than does the 

 striated muscle. 



I have also found that both smooth and striated muscle gain 

 weight rapidly in isotonic solutions of glycerine and urea, but I 

 have not thought it worth while to publish detailed accounts of 

 the experiments with these substances, as the two tissues soon 

 lose their irritability in solutions of them. The striated muscle 

 goes into rigor, while the fibers of smooth muscle lengthen enor- 

 mously. In a few cases preparations of striated and smooth 

 muscle have been immersed in hypertonic solutions of dextrose 

 and cane sugar (Experiments 21, 22, 49, 50, 70 and 71). The 

 striated muscle tends to lose weight in such solutions, while the 

 smooth muscle gains weight, though not quite so fast as in the 

 isotonic solutions. The behavior of the smooth muscle in these 

 sugar solutions is, however, rather capricious. If Experiment 50 

 be compared with Experiment 71, it will be noticed that the mus- 

 cle in the stronger solution has gained a larger percentage of its 

 original weight at the end of two hours than the muscle in the 

 weaker solution. 



