252 ARTHUR WILLIAM MEYER 



IjTnph glands, seemed wholly conflicting, a series of experiments 

 on dogs and guinea-pigs was undertaken in connection with 

 studies on hemohmph nodes of domestic animals. Ten dogs 

 taken from two litters with known dates of birth were placed 

 under laboratory conditions as soon as weaned, kept in identi- 

 cal surroundings and fed upon the same food until approximatelj'- 

 six months old. The spleen was then removed from eight, one 

 animal from each litter being kept as a control. Before remov- 

 ing the spleen the omenta, mesentery and as far as possible also 

 the whole abdominal cavity, were inspected in order to note the 

 condition of the lymph nodes and the presence of accessory 

 spleens. After operation the animals were again kept under iden- 

 tical conditions and killed 41 to 126 days later, one animal being 

 killed every two weeks. The spleens were inspected for scars 

 and weighed. Recovery in every case was rapid and healing 

 per priman except in one dog in which several small cutaneous 

 stitch-abscesses developed. There were no adhesions in any ani- 

 mal. All of them gained markedly in weight not only because 

 they grew rapidly but because they became fleshy and some 

 even fat. Table 1 gives the age, the post-operative period and 

 the result. The gain in weight is not given because it could 

 have no special significance since all were young and growing 

 dogs. 



As is evident from the table, the results on these dogs fully 

 confirm those of Vincent and of many operators on man. Only 

 a single lymph node with a reddened center and 3.5 mm. in size, 

 was found in the gastro-splenic omentum of one dog at the time, 

 of operation. No hemal nodes or accessory spleens were seen 

 before or after operation, and it is especially interesting that the 

 above node became paler or at least was temporarily paler, at 

 the tirfie of necropsy fifty-three days after operation. Although 

 it could not be experimentally determined before or at the time 

 of operation, whether the pinkish node was lymphatic or hemal 

 in character this precaution was not neglected at the t^me of 

 necropsy. All questionable appearing nodes which suggested 

 intermediate forms were injected, but not a single hemal node 

 was found. Since all nodes except those on the head, dorsum 



