DAVID CREWS (Department of Zoology, University of California, Berkeley, 
California 94720) continues to study the psychobiology of reproduction in 
Anolis carolinensis 
His findings to date have been: 
l. Female receptivity correlates with stages of follicular maturation, 
sexual receptivity being restricted to a period preceding ovulation and 
dependent on hormonal conditions arising during the course of follicular 
maturation. Thus during the breeding season, receptivity, like the 
follicular cycles, is rhythmic. 
2. In more recent investigations of the relationship between female 
sexual receptivity and the pattern of secretion of ovarian hormones during 
the follicular cycle, Paul Licht and Crews have developed a radioimmunoassay 
for measuring concentrations of estradiol and progesterone in the peripheral 
plasma, Although sample sizes are to date small, it appears that estradiol 
titer increases as the follicle matures while progesterone is highest after 
ovulation, 
3, In related experiments, Michael Budin and Crews have been trying 
to determine the minimum effective dosage of estradiol benzoate (EB) 
necessary for reinstating sexual receptivity in ovariectomized females, 
They find that a single injection of .8 micrograms of EB will make at least 
50% of the females receptive to male courtship while as little as .1 
microgram/day will rapidly induce (in three days) and maintain receptivity. 
. Mating abolishes receptivity until the preovulatory stage of the 
next follicular cycle. Mating must be completed to affect receptivity. 
5. Male courtship acts along with environmental stimuli to induce 
ovarian recrudescence in winter-dormant females, 
6. Male-male aggression inhibits the environmental induction of 
ovarian recrudescence, Non-specific stress, e.g. handling by the experi- 
menter, does not. 
7, Castration abolishes male courtship behavior, hence preventing 
male courtship facilitation of ovarian recrudescence. Androgen replacement 
therapy restores male courtship behavior in castrated males and consequently 
courtship facilitation of ovarian recrudescence. 
8. The critical cue for both long-term courtship facilitation of 
ovarian recrudescence and short-term behavioral responsiveness of receptive 
females to male courtship is the ability of the male to extend the dewlap, 
thus changing the body profile, and not dewlap color. 
9. Paul Licht and Crews have found that the corpora atretica render the 
female insensitive to both environmental and hormonal stimulation and probably 
function to maintain the refractory period following the breeding season. 
