206 MALL. [Vor. XIX. 
of development of the embryo indicate that the pathological 
changes began not later than the sixth week of pregnancy, 
while the menstrual history of the mother indicates that at 
least 14 weeks have elapsed between the conception and the 
abortion. In other words, the pathological process has been 
under way for at least eight weeks. The extreme changes 
within the embryo also speak for this. The nervous system 
is markedly dissociated and macerated. Arms and legs, ex- 
ternal features, as well as most of the internal organs, have 
vanished. ‘The liver is still marked, but is necrotic. Wander- 
ing cells have invaded all of the tissues and are also beginning 
to attack the cartilaginous bodies of the vertebra. Large 
nests of them are also imbedded in the clots of blood which 
surround the embryo. The main blood-vessels of the embryo 
can still be traced through the surrounding tissues. The cord 
is filled with embryo’s blood, but this is also necrotic. 
From all appearances had this ovum remained in the uterus 
much longer it would soon have become filled with mother’s 
blood, which in turn would soon have solidified to make of 
the specimen a typical fleshy mole. 
Fic. 143.—Photograph of the vesicle. Natural size. 
No. 143. 
Large double sac, 15 x 10 mm., attached to the wall of the 
chorion. 
Dr. Stick, Glenville, Pa. 
The chorion appears normal. The double cyst-like body 
has thin walls and is filled with a clear fluid. The specimen 
has been in strong alcohol for nearly twenty years. 
Serial sections show a chorion, normal in appearance, to 
which is attached the double vesicle as shown in the photo- 
