No. 1.] ORIGIN OF HUMAN MONSTERS. 215 
fragments of villi which remain are imbedded in blood and 
are riddled with the cells of the syncytial layer. The meso- 
dermal layer of the chorion is no longer sharply defined and 
is more or less filled with cells with fragmented nuclei, the 
origin of which cannot be determined. 
The embryo is of the stage of five or six weeks with pretty 
sharply defined organs and tissues which are more or less dis- 
sociated and infiltrated with wandering cells. Most of the 
epidermis has fallen off; in the region of the olfactory pit 
(which is almost obliterated) the epidermis forms two marked 
horn-like elevations. The central nervous system is swollen 
and dissociated more than the remaining tissues of the body, 
the change being greater in the brain than in the cord. The 
vascular system is gorged with blood which is beginning to 
invade the surrounding tissues. This increase is most marked 
in the umbilical cord, which appears cedematous. 
No. 177. 
Embryo, C. R., 12 mm. 
Dr. Harrison, Baltimore. 
The sections show well outlined all of the organs of an 
embryo of the end of the fifth week, but they are dissociated 
and swollen. So extensive is the dissociation in the head that 
the brain has become practically solid, the vesicles being nearly 
obliterated. The process is not so extensive in the spinal cord. 
Most of the epidermis has fallen off. 
The vascular system is again greatly distended with blood 
which is infiltrating the tissues, especially those surrounding 
Fic. 177—The photograph shows the rounded head and stubby leg. En- 
larged 2 diameters. 
