228 MALL. [Vo.. XIX. 
The thoracic region, liver and vascular system have under- 
gone practically no change. The extensive growth of meso- 
dermal tissue throughout the embryo has caused an extensive 
destruction and arrest of further development of the muscular 
system. This is shown by all kinds of secondary changes in 
the connective tissue, especially that of the skin, which 1s 
markedly fibrous, as may be seen in Fig. 2o1e. Here the 
change is so great that it obliterates the external auditory 
canal entirely. 
No. 204. 
Ovum, I4 x 12 x 8 mm. 
Dr. D. S. Lamb, Washington. 
The specimen, said to be three weeks old, was found filled 
with a mass of granular magma. The whole ovum was 
stained and cut, but no trace of an embryo could be found. 
The chorion and villi appear normal. 
No. 205. 
Ovum, 40 x x30 x 30 mm.; embryo, C. R., 6 mm. 
Dr. D. S. Lamb, Washington. 
“The specimen is about four weeks old and is from a 
woman who had been married three months. Syphilis is 
suspected in the case.”’ 
The chorion is partly encircled with the decidua, which is 
more or less necrotic and well infiltrated with leucocytes, 
showing that an inflammatory process was present in the 
uterus. The chorion is fibrous at points and at others cedem- 
atous, with but few blood-vessels present. The villi are 
irregular and often very fibrous, being hypertrophied as well 
as atrophied. Their outlines are irregular and they are cov- 
ered with a dense and very irregular mass of syncytial cells. 
But few of the villi have blood-vessels within them and they 
are all empty. 
The amnion is completely adherent to the chorion through- 
out its extent, making these two membranes appear as one. 
On the amnion side there are numerous fibrous tuberosities 
