238 MALL. [Vor. XIX. 
The cavity of chorion is lined with a very thick amnion 
and the remnant of an embryo indicates that its development 
was arrested towards the end of the third week. The de- 
forming process must have been active for at least 50 days. 
The vascular system is still represented by a mass of cells 
on the ventral side of the embryo, behind which there is a 
large vessel full of blood extending towards the remnant of 
the umbilical vesicle. No vessels extend to the chorion. 
The central nervous system fills the main part of the em- 
bryo, being much dilated in the head and pretty well filled with 
round cells throughout. In front of the brain are two vesicles 
which communicate with it through two long tubes. These 
no doubt represent the eyes. In the neck there is a small 
gland, possibly the thyroid. 
No. 230. 
Ovum; 75 x 60 x 5o mm. "embryo, ©. Ry 57 mm. 
Dr. West, Bellaire, Ohio. 
“The mother has had three children and three miscarriages. 
She always menstruates regularly during her pregnancy, and 
she has been undecided during the past seven months whether 
or not she was pregnant.” 
Upon opening the ovum it was found that the foetus is 
greatly cramped and imbedded in much granular magma. 
The cord is thin and knotted. The right leg has a club-foot 
and the left has a dislocated knee-joint. Evidently the em- 
bryo has been dead for a long time. 
The tissues of the embryo and membranes appear normal; 
they barely stain at all. The outer zones of the chorion are 
slightly infiltrated with leucocytes. 
The dislocated knee and the club-foot show that the car- 
tilages are markedly deformed, but on account of the absence 
of tissue reactions it must be concluded that this change took 
place after the death of the embryo. The liver, brain, spinai 
cord and eye are macerated, converted into a pulpy mass and 
do not stain. All of the epidermis has fallen off. Appar- 
ently the embryo died suddenly, for there are practically no 
tissue reactions to suggest the contrary. 3 
