No: 1.] ORIGIN OF HUMAN MONSTERS. 249 
The tissues of the embryo, however, and the cavity of the 
front end of the brain are filled with numerous small round 
cells wth fragmented nuclei. All stages of fragmentation are 
seen, just as may be seen in the leucocytes in small abscesses. 
Most of the red blood cells are within the blood-vessels, but 
those within the tissues appear perfectly normal. On account 
of the diminished number of mesoderm cells, in fact, they 
<— 
Fic. 250e.—The dotted area in the section shows the portion which is 
enlarged in Fig. 250d. 
diminish in proportion to the number of fragmented cells 
present, the conclusion must be drawn that the latter arise 
from the former. The epidermis covers the whole embryo. 
The primary change in this specimen is no doubt in the 
mesoderm, for all the rest of the embryo appears normal. 
That the equilibrium was overthrown is indicated by the 
necrotic amnion and the great amount of reticular magma in 
the exoccelom. 
No. 251. 
Ovum, 30 x 25 x 25 mm.; embryo, C. R., 9g mm. 
Dr. Ritter, Brooklyn. 
Last period January 16, abortion April 3. Half of the 
chorion is covered with villi and the other half is bare, thick- 
ened and hemorrhagic. The amnion lines the entire chorion 
and the cord is very thin. Sections show that the mesoderm 
of the villi are rich in cells, fibrous and are devoid of blood- 
vessels. The main wall of the chorion is apparently normal, 
with a large number of vessels filled with blood scattered 
through it. The decidua is very extensive, is hemorrhagic 
and has a large number of abscesses in it. Apparently there 
was an extensive endometritis. 
