No. 1.] ORIGIN OF HUMAN MONSTERS. 321 
No. 330. 
330A. Ovum, 60 x 55 x 50 mm.; embryo, C. R., 12 mm. 
330B. Ovum, 55 x 50 x 45 mm.; embryo, C. R., 12 mm. 
Dr. West, Bellaire, Ohio. 
“The woman from whom these twin specimens were ob- 
tained is about 25 years of age. Fifteen months ago she gave 
birth to an eight-months child, which lived for two days. Her 
last regular menstrual period took place during the middle 
of September. The October and November periods were 
missed. About the middle of December, at her regular time, 
bleeding began, which continued until January 21, when these 
two ova were aborted. I am quite positive, but not certain, 
that woman has syphilis.”’ 
Both ova have smooth surfaces, being composed of thin 
walls, upon which there are occasional villi. In both speci- 
mens the villi are imbedded in a mass of pus, in which may 
be found irregular villi, much necrotic syncytium, fibrin and 
blood. Many leucocytes are found in the mesoderm of the 
villi. The main wall of the chorion and the amnion of both 
specimens are of irregular thickness and are well blended with 
each other. 
The changes in the two embryos are very similar. In both 
the epidermis is intact and the dermis is thickened. In front 
of the head in the region of the deformed mouth there are 
peculiar thickenings of the epidermis. Both spinal cords are 
markedly dissociated. The dissociation of the brains is so 
extensive that in consequence the cerebral vesicles and mid- 
brains are nearly destroyed and the hind-brains occupy spaces 
in the centers of the deformed heads. 
The large vessels and heart are gorged with blood. In B 
the wall of the ventricle is well infiltrated and in A nearly 
destroyed by the migrating cells. The outlines of the organs 
and tissues are very obscure, the whole being more or less 
filled with round cells. Some of the liver tissue is necrotic. 
No. 334. 
Fleshy mole, 50 x 40 x 30 mm.; embryo, 5 mm. 
Dr. Merrill, Stillwater, Minn. 4 
