No. 1.] ORIGIN OF HUMAN MONSTERS. 353 
well filled with blood-vessels from the embryonic mass, which 
must have been present at one time. 
No. 375. 
Embryo, C. R., 13 mm. 
Professor Gage, Ithaca, N. Y. 
A piece of chorion accompanied the embryo, both of which 
appear quite normal. However, sections of the chorion show 
that the mesoderm of the villi is very fibrous, while that of its 
main wall appears normal. The syncytium seems to be defi- 
cient in quantity. 
Sections of the embryo indicate that it is nearly normal, 
with some dissociation of the tissues. The larger blood-ves- 
sels are gorged with blood, and some of the tissues, especially 
those in front of the head, are infiltrated with round cells. 
The central nervous system is swollen and dissociated, as is 
so frequently the case in many of the other embryos. 
No. 377a. 
Ovum, 30 x 22 x 14 mm. 
Dr. Crawford, Cedar Rapids, Iowa. 
The specimen is well covered with villi, which appear quite 
normal to the naked eye, but upon microscopic examination 
it is found that they are very fibrous and tipped with syn- 
cytium; at points it forms islands with necrotic centers. 
The interior of the ovum contains a considerable amount 
of reticular magma, within which there is embedded a large 
sac (5 mm. in diameter) containing a nodule (.5 mm. in 
diameter )—the embryo. 
Sections show that the whole chorion is lined with the 
amnion except at the point of the “inclosed sac,” which proves 
to be the exoceelom. The embryo is composed of an amor- 
phous mass of cells which invade the mesoderm of the chorion. 
It may represent the last remnant of the umbilical vesicle. 
No traces of blood-vessels are seen in any portion of the 
embryonic mass, nor in the mesoderm of the chorion. 
