Hata, Mitosts in Nerve Cells. 281 
4 X 3.6 micra to 6.3 X 6.3 micra in diameter. Moreover, germ- 
inal cells contain chromosomes more deeply stained than those 
of the resting epithelial cells, presenting bluish red tints after 
HERMANN’S method. 
The cell-body, as well as the nuclear membrane, is distinctly 
visible in the germinal cells. The chromosomes occur in great 
abundance and are distributed throughout the nucleus. The 
linin is clearly distinguishable from the rest of the other struc- 
tures, while in the epithelial cell, it is extremely hard to distin- 
guish it. The most conspicuous, as well as most important 
changes in this phase, are-the nucleolar movements. In the 
inactive epithelial cell, the nucleolus appears as a compact and 
homogeneous structure, lying within the nucleus (Fig. 24). 
This simple structure, however, separates into numerous gran- 
ules, owing toa solution of the linin which intimately surrounds 
the nucleolus in its resting stage (Fig. 24). The structural 
relations of these small granules in the nucleolus will be dis- 
cussed later. 
Following this stage just mentioned, a most remarkable 
change is exhibited by the chromosomes." 
As figure 2 shows, the chromatic granules enlarge coneiee 
erably, and at the same time a diminution in. the number of the 
granules takes place. The chromosomes in this stage stain 
more intensely than in the first case, and also the reddish color 
predominates over the bluish (HERMANN’s method). The cell- 
membrane, the nuclear membrane, and the nucleolus, are 
clearly visible, although in some cases, the nucleolus dissolves 
into numerous minute corpuscles. The linin network, in which 
‘the chromatin granules are suspended in the resting stage, be- 
comes distinct. The centrosome lies at one side close to the 
nucleus. ; 
Fig. 3 shows some very important changes of the chrom- 
atic granules. The chromatic granules, which are scattered 
throughout the nucleus in the former stages, now arrange them- 
1 In this stage the cell-body, measures about 9 X 6.3 micra to 12.6 & 7 in 
diameter, while nucleus measures 5.4 X 5.7 micra to 11.7 X 7 respectively. 
