152 



RAYMOND PEARL 



With these pedigrees in hand it is desirable and possible to 

 answer certain questions which arise in the mind of any experi- 

 enced geneticist in connection with experiments of the sort 

 here under discussion. Some of the more important of these 

 are (a) To what degree is the foundation stock inbred? (b) 

 Does the foundation stock represent a relatively wide or a rela- 

 tively narrow range of hnes of descent (blood Unes)? (c) Can 

 the foundation stock be regarded as a fair random sample of 

 the general population from which it was drawn? 



Let us consider these points in order. Fortunately we are 

 able, by means of the coefficients of inbreeding devised by the 

 writer, to give precise and definite numerical statements regard- 

 ing the degree of inbreeding exhibited by this foundation stock. 

 These coefficients are shown in table 3. 



TABLE 3 



Inbreeding coefficients of stock used in alcohol experiments, with comparison data 



