152 CARL R. MOORE 



mal manner. 1^ Inasmuch as the ovary at the time of trans- 

 plantation was cut into two pieces, and these probably never of 

 the same size, it was impossible to ascertain the amount of growth 

 in any specific piece. The stroma tissue is quite characteristic 

 of the normal ovary. Both mature and immature Graafian 

 follicles are abundant and some contain ova apparently ready 

 for ovulation. That ovulation really does occur is shown by 

 the presence of a few corpora lutea, some of which still contain a 

 blood clot in the center. Many Graafian follicles indicate an 

 evident tendency for degeneration, and atretic follicles are often 

 found in the preparations. Reference to figure 1 will convince 

 one that the ovarian cortex, stroma, and contained follicles as 

 well as the medulla of the ovary are retained in apparently a 

 normal condition. This section is a piece of the original young 

 ovary placed subcutaneously in the male at the age of thirty 

 days and allowed to grow until the animal was killed 230 days 

 later. Vascular connections may be established either from 

 cutaneous blood-vessels or in case of a deeper transplantation 

 by vessels supplying the abdominal muscles. This graft was 

 imbedded in the superficial fascia. The section passes through 

 the ovum of two mature follicles and each contains a very dis- 

 tinct nucleus. Figure 2 (from same graft as fig. 1) shows not 

 only the more mature follicles, but a young follicle as well as a 

 corpus luteum. The graft from which these two sections were 

 prepared had persisted throughout the entire period of the ex- 

 periment in almost a normal condition. It was physiologically 

 active, since the germinal epithelium shows an apparently normal 

 condition, young follicles are present also mature follicles evi- 

 dently almost ready for ovulation, and corpora lutea are present, 

 showing that a previous o\'ulation has taken place. The con- 

 dition of this graft can represent the general condition of the 

 persisting grafts, since no other features worthy of mention 

 have been noted in other grafts. 



'5 In several cases of transplantation of both ovaries and testis, more espe- 

 cially testis, the glands failed to persist and underwent resorption, leaving little 

 if any traces of the original implantation. 



