80 M. F. GUYER AND E. A. SMITH 



after birth, No. 4 ate one of hers, and No. 5 lost one of hers at 

 the end of the first week. Thus, only five young of the females 

 treated with sensitized serum survived long enough to get their 

 eyes open. 



Viewed externally, the eyes of these five young appeared 

 normal. All showed the usual heavy pigmentation and no de- 

 fects were apparent in the lenses. On May 23 all were decapi- 

 tated, the eyes were removed immediately and the lenses care- 

 fully dissected out. In this way abnormalities which were invisi- 

 ble in the living animals came to light. 



One of the young of No. 3 had both lenses normal in consist- 

 ency and transparency, the other one had the left lens normal, 

 the right markedly clouded. One of the young of No. 4 had both 

 lenses translucent, the other one had an opaque zone around the 

 periphery of the left lens and a relatively large, scar-like white 

 area in the right. From table 5 it will be noted that parents 3 

 and 4 had received only one dose of the sensitized serum, and 

 that late in pregnancy. T^he remaining young one, from a 

 mouse (No. 5) which had been given two doses of the serum 

 had both lenses affected, the left being opaque and abnormally 

 small, the right transparent but of a liquid instead of the nor- 

 mal fibrous consistency. The entire eyeball in fact, which con- 

 tained the dwarfed lens was upon removal readily seen to be 

 smaller than the other eyeball, or than that of a normal mouse 

 of the same age. 



The four young of the surviving injected control, No. 11, were 

 killed the same day and were found to have lenses of normal 

 size, texture, and transparency. It would appear, therefore, 

 that unsensitized fowl serum has no perceptible effect on the 

 lenses of the unborn young. 



As a further control, six normal young, two sixteen days old 

 with eyes just opened, and four fifteen days old with eyes not 

 yet open, were also killed and examined. Their lenses were all 

 transparent and of fairly firm texture. 



The lenses of the treated mothers were also carefully exam- 

 ined, but all had remained of normal consistency and trans- 

 parency. 



