FEEDING SUDAN III TO YOUNG ALBINO RATS 



109 



TABLE 3 



Showing the growth of the organs of the albino rat as affected by the feeding of Sudan 

 III. Dose 8 to 9 mgms. Older series 



LENGTH = MM. 

 WEIGHT = GB.4M.S 



Body length. 

 Tail length.. 

 Body weight 



Brain 



Kidneys 



Liver 



Spleen 



Pancreas. . . . 



Thymus 



Suprarenals . 



Thyroid 



Hypophysis . 



Testes 



Ovaries 



Age (days).. 



2 cf + 3 9 



155.2 



139.4 

 98.4 

 1.59S 

 0.794 

 3.861 

 0.550 

 0.703 

 0.273 

 0.023 

 0.020 

 0.0040 

 1.262 

 0.0152 



64 



From table 2 we note that despite the fact of almost no growth 

 of the entire body of the test animals, such organs as the hver 

 and pancreas made a striking increase in weight throughout the 

 entire period of the Sudan III feeding. On the other hand, the 

 thymus gland was greatly atrophied, and the sex glands also 

 showed a marked diminution in weight. None of the other organs 

 showed noticeable loss when compared with those of the rats 

 examined at the beginning of the experiment. 



These alterations just noted appear also in the second series 

 of the experiments (table 3), where a much smaller dose of Sudan 

 III (8-9 milHgrams) has been given. I may add here that al- 

 though on the average the kidney weights of the Sudan-fed rats 

 do not differ much from their initial weights, nevertheless the 

 individual records show that in the majority of cases the kidneys 

 of the test rats have suffered a slight atrophy. I am thus inclined 

 to believe that the kidneys also undergo a slight atrophy as the 



