no 



S. HATAI 



TABLE 4 



The iveights of the organs determined in both control and Sudan III fed rats at the 



end of the experiment 



result of feeding Sudan III. Some of the organs, however, in- 

 crease in weight. The increase of the hver in weight seems to be 

 due to an accumulation of fat, as this can be shown histologi- 

 cally, as well as by the amount of lipoids extracted (page 113). 

 The increased weight shown by the pancreas may be due to the 

 hyperactivity of this organ in connection with the metabolism 

 of fat. 



The atrophy of the thymus gland as the result of feeding 

 Sudan III is most noticeable. The rate of thymus atrophy seems 

 to depend on the amount of Sudan III administered. A larger 

 dose appears to reduce the thymus much more quickly than a 

 smaller dose. Since the thymus is highly sensitive to almost 

 any abnormal physiological condition, such as an exposure to 

 Roentgen rays, inanition, etc., we may assume that the present 



