THE BLOOD SUPPLY OF THE PITUITARY BODY 



WALTER E. DANDY and EMIL GOETSCH 



From the Hunterian Laboratory of Experimental Medicine, The Johns 



Hopkins University 



FOUR FIGURES 



INTRODUCTION 



Studies made in the Hunterian Laboratory^ by Reford, 

 Crowe, Homans, Goetsch and Gushing, based upon a series of 

 over two hundred canine and feline hypophysectomies, have 

 supported Paulesco's view that a fragment of the pars anterior 

 is essential to the maintenance of life, a total hypophysectomy 

 being invariably fatal in the course of a few days, the length of sur- 

 vival depending somewhat upon the age of the animal. Durmg 

 the course of these investigations it was found that the gland could 

 be separated from its dural pocket and left dangling by the stalk 

 alone without destroying its vitality. Division or ligation of the 

 stalk, on the other hand, often led to profound histological altera- 

 tionsi evidently due to an ansemic necrosis confined largely to the 



1 (1) Is the pituary gland essential to the maintenance of life? The Johns 



Hopkins Hasp. Bull., 1909, 20, no. 217. .. ., • , f 



(2) The hypophysis cerebri: clinical aspects of hyperpituitarism and ot 



hypopituitarism. J. Am. Med. Ass., 1909, 53, p. 249. , , _„ 



' (3) Effects of hypophyseal transplantation following total hypophysectomy 



in the canine. Quart. J. Exper. Physiol., 1909, 2, p. 389 



(4) The functions of the pituitary body. Am. J. Med. bci.l9W. 



(5) Experimental hypophysectomy. The Johns Hopkins Hosp. Bull, 1910, 



^^' ^e/^ Concerning the secretion of the infundibular lobe of the pituitary body 

 and its presence in the cerebrospinal fluid. Am. J. of Physiol, 1910, 2,, 

 p. 60. 



The American Journal of Anatomy, Vol. 11, No. 



