30 TADACHIKA MINOURA 



condition are: embryos nos. 27-6, 31-3, 47-10, 43-3, among those 

 grafted with testis, and nos. 27-4, 7-3, and 7-4, among those 

 grafted with ovary. This condition represents a mixture of the 

 characters of the two sexes. 



3. It is important to note that the intersexual condition 

 described under 2, where male-type gonads are combined with 

 female-type mtillerian ducts differs according to the kind of 

 gonad grafted on the embryo in question. In the case of testis 

 grafts, these intersexual embryos have gonads of the male type; 

 that is to say, the two gonads are nearly of the same size. Ex- 

 amples: embryos nos. 27-6, 31-3, 47-10, 43-3, 27-5. On the 

 other hand, such intersexual embryos when produced by ovary 

 grafts have gonads which resemble ovaries; that is, the left gonad 

 is considerably larger than the right one. Examples: embryos 

 nos. 27-4, 7-3, 2-5. Not only are the gonads of the intersexual 

 embryos different in size in such cases, but the shape and texture 

 of the left ovary differs from that of the right, bearing a greater 

 resemblance to the normal left ovary. The condition of the 

 mtillerian ducts in the intersexual embryos is also related to the 

 kind of gonad which was responsible for the intersexual con- 

 dition. Where the grafted gonad was a testis, the miillerian 

 ducts of the affected embryos are undifferentiated (nos. 47-10, 

 43-3) and show signs of degeneration (as in nos. 27-6, 31-3, 

 27-5). Intersexual embryos produced by ovary grafts, on the 

 other hand, retain the miillerian ducts, degenerative changes in 

 the ducts are absent, and the left duct is better developed and 

 more differentiated than the right one (nos. 27-4, 7-4, 2-5). 



4. The right gonad of female-type embryos is larger than that 

 of the normal female. The right ovary normally develops to 

 a length of 1.5 to 2 mm., and then degenerates and disappears 

 (table 4) . On the other hand, in several of the affected embryos, 

 the right gonad measures more than 3 mm., and in a few cases 

 even more, as 3.3 mm. in embryo no. 17-7, 3.5 mm. in embryo 

 no. 30-9, and 4 mm. in embryo no. 30-6. The right gonad in 

 these embryos has a definite outline as compared with the fading 

 outlines of the normal degenerating right ovary, and it resembles 

 a rudimentary or degenerating testis. 



