132 CARL R. MOORE 



mained intact if the peritoneal capsule surrounding the ovary 

 is carried over with the transplant. The majority of Graafian 

 follicles became degenerate very early, but in two instances 

 normal follicles were found in the graft a month or little more 

 after the transplantation was made. The ova degenerated 

 before other parts of the ovary, and out of all cases examined 

 but one ovum was found after a period of forty-two days : thirty- 

 nine cases were negative in regard to the presence of normal ova 

 in the grafts. Herlitzka attempts to account for this early 

 degeneration of ova by assuming that the ovum is the most 

 specialized part of the tissue and that the specialized tissue 

 is the first to suffer in a strange environment. The author's 

 general conclusions of antagonistic influences of sex glands are 

 that the presence of the testis does not impede or interfere with 

 the vitality of ovarian tissue. However, this investigator was 

 not able to obtain good persistence of tissue even in autoplastic 

 grafts (removal of ovary to another position within the same 

 animal) ; hence his results, little better than negative evidence, 

 shed little light upon a possible antagonism. He is of the opinion 

 that Schultz utilized young animals for his experiments, for 

 Herlitzka' s impressions are that adult ovaries will not persist 

 after transplantation. 



Schultz ('00) reports five positive cases of ovaries transplanted 

 into males with the transplanted ovary retaining its character- 

 istics in quite a normal condition. He mentions no negative 

 cases and neither does he state whether the animals were young 

 or adult. Possibly they were young animals, and Foa ('00) has 

 shown that there is great possibility of persistence if the trans- 

 plants are made at an early date. 



Marshall and Jolly ('08) transplanted ovaries of rats from one 

 position to another in the same animal, as well as from one rat 

 to another. Considerable success attended their efforts, as 

 grafts after five to eight months showed the presence of follicles 

 and corpora lutea. One attempt was made to graft an ovary 

 into a male rat (presumably with testis present), according to 

 them, "with some success The graft showed recog- 

 nisable ovarian tissue in parts, but had undergone very con- 



