164 CARL R. MOORE 



peritoneal graft, but no subcutaneous graft (female had given birth 

 to a litter). Tissue not sectioned. 



Animal 51 B. Female, born Feb. 27, '18. April 16, one ovary- 

 removed, testis from brother grafted subcutaneously and intraperi- 

 toneally. Aug. 22, '18, killed (suckling litter when killed); right ovary 

 normal, both grafts persisted. 



Graft 1 consists mostly of scar tissue and connective tissue. 

 The greater part of this graft has been resorbed, but here and 

 there are the distinctly well-rounded, degenerating seminiferous 

 tubules containing only the Sertoli cells and the reticular net- 

 work. The tubules are not collapsed and but little if any inter- 

 stitial tissue is present. 



Graft 2 likewise contains but little of the original testis tissue 

 implanted. The tubules present are similar to the tubules in 

 all the grafts so described, whether the remaining tissue is 

 abundant or consists only of a few scattered tubules. Nothing 

 beyond what has been previously described is worthy of note. 



Animal 51 C. Female, born Feb. 27, '18. April 13, left ovary 

 removed, testis from brother placed subcutaneously and intraperi- 

 toneally. Aug. 22, '18, killed; right ovary normal, both grafts persisted 

 (had given birth to a litter) . 



Graft 1 consists of an elongated strand of seminiferous tubules 

 that are present in 250 sections; some cross-sections will show 

 only four or five sections of these tubules, while others may 

 show as many as fifteen or twenty sections of the tubules. These 

 merit no especial description, as they differ from the others in 

 no essential features. 



Graft 2 for the greater part has been resorbed. Here also the 

 remaining tubules are imbedded in the muscular or connective 

 tissue and are entirely similar to the tubules of all other grafts. 



VI. DISCUSSION 



After a consideration of such a group of grafts as those de- 

 scribed, it is perfectly evident that pieces of ovaries and testes 

 can be successfully grafted into an animal of the opposite sex 

 possessing one of its normal sex glands, and that these grafts 

 may persist for a period of eight and one-half months in a normal 



