AUTHORS' ABSTRACT OP THIS PAPER ISSUED 

 BY THE BIBLIOGRAPHIC SERVICE, MARCH 14 



ALCOHOLISM AND THE BEHAVIOR OF WHITE RATS 



I. THE INFLUENCE OF ALCOHOLIC GRANDPARENTS UPON 

 MAZE-BEHAVIOR^ 



E. C. MACDOWELL AND E. M. VICARI 



Station for Experimental Evolution, Cold Spring Harbor, Long Island, New York 



SEVENTEEN FIGURES 



CONTENTS 



Introduction 210 



Methods 211 



a. Source of material 211 



b. Alcoholization of the grandparents 213 



c. The alcohol tanks 214 



d. Training; apparatus and methods 214 



e. 'Failures,' 'completes' and 'incompletes' 215 



/. Irregularities of data 218 



g. Criteria employed ; 220 



Results 220 



1. Morphological changes 220 



2. Comparison of the test and control rats on the basis of time 221 



a. Time : averages for different groups of trials 221 



b. Time : averages for each day 229 



c. Variabilitjr of the tests vs. controls judged by time 240 



d. What is the probability that the test data and the control data 



. for time are not random samples from the same population? 243 



e. Conclusions based on the time data 244 



3. Comparison of the test and control rats on the basis of the distance 



covered in running each trial 246 



a. Distance: averages for different groups of trials 246 



b. Distance : averages for each day 250 



c. Variability of the tests vs. controls judged by distance 258 



d. What is the probability that the test data and the control data 



for distance are not random samples from the same population? 260 



e. Summary of results from the distance data 262 



/. Correlation between time and distance data 262 



1 This is one of a series of papers on the general subject. Following studies 

 will cover the results of training these same rats upon a multiple-choice appar- 

 atus, and of training the parental and grandparental generations. 



209 



THE JOURNAL OF EXPERIMENTAL ZOOLOGY, VOL. 33, NO. 1 v 



