AtPTHOB'S ABSTRACT OF THIS PAPER ISSUED 

 BY THE BIBLIOGRAPHIC SERVICE, MAT 23 



ON THE PHYSIOLOGICAL PROPERTIES OF THE 

 GONADS AS CONTROLLERS OF SOMATIC AND 

 PSYCHICAL CHARACTERISTICS 



IV. GONAD TRANSPLANTATION IN THE GUINEA-PIG 



CARL R. MOORE 



The University of Chicago 



FOUR FIGURES 



INTRODUCTION 



In former papers^ the writer has presented certain observations 

 on the effect of gonad transplantation in young castrated animals 

 of the opposite sex; all observations so far considered refer to the 

 white rat. A similar group of experiments, using the guinea-pig 

 as the experimental animal, were begun before the previous exper- 

 iments were brought to a close, and a report of these latter exper- 

 iments is embodied in the present paper. The experiments were 

 conducted in order to study the physiological effect of the internal 

 secretions of the gonads on the somatic and psychical charac- 

 teristics of the animals. 



Since 1910 Steinach has published several papers on his study 

 of the internal secretions of the gonads and their influence upon 

 somatic and psychical differentiation in the rat and guinea-pig. 

 By transplanting gonads from one young animal to one of the 

 opposite sex (rats and guinea-pigs), the latter having its own sex 

 glands removed, he maintains, 1) that a young female becomes 

 masculinized as it grows to an adult and, 2) that a young male in 

 like manner is converted unto a female-like animal. In this trans- 

 formation the 'masculinized female' grows to a larger size, in- 

 creasing in weight relative to other spayed females not receiving 

 testicular grafts: the hair coat becomes male-like: the skeleton 

 is different from that of a female : the condition of the fat deposit 



1 See Moore, '19, '20. 



365 



