382 



CARL E. MOORE 



The tubules are not so compactly arranged as in the normal 

 condition, but are widely separated and the intertubular spaces 

 are filled with interstitial cells. These cells are distinct, well 

 stained, and large, and apparently there has been an hypertrophy 

 of the interstitial tissue. The cells are present in an abundance, 

 filling completely the large spaces between adjacent tubles. The 

 conditions are relatively the same for the two grafts. 







i^^^M f ^ 











Jf 







';^: 





ic 



Fig. 4 Part of cross-section of testis graft from female guinea-pig (68 B 1), 

 seven months after transplantation (same animal, but different graft from fig. 3). 

 2c, interstitial cells; st, seminiferous tubule. 



The reason for the difference between the grafts from the two 

 animals is not clear. That of 67 Bl has persisted for nine months 

 and was slightly larger than in 68 Bl : the germinal epithelium of 

 the former was not nearly so much affected as in the latter and 

 the tubules were more compactly arranged: there was little or 

 no increase in the interstitial cells of the former, while in 68 Bl 

 the tubules are widely separated by a very prominent mass of inter- 



