188 HAROLD J. COOPER 



The pars neuralis in the mammalia is made up chiefly of 

 ependyma and glia cells, among which run many fibers. Mtiller 

 ('71) regards this portion as one reduced in structure to a con- 

 nective-tissue appendage of the brain. Berkley ('94) describes 

 an elaborate arrangement of nervous elements, but his paper 

 stands quite without substantiation from the later writers. It 

 is not generally considered that there are any true nerve cells in 

 the nervous lobe. Nerve fibers exist in great abundance as 

 described by Herring and others. Clunet and Jonnesco ('10) 

 studied in detail the pigment of this lobe, which occurs especially 

 in the higher mammals. 



The existence of colloid matter in the various portions of the 

 gland is given mention in many references, but the best accounts 

 are to be found in the works of Herring, Stendell, and Biedl. 

 Steida ('90) states that the colloid in the pars distalis is found 

 within the chromophile cells. In the pars infundibularis it 

 may be in the cells or gathered into cysts. Benda believes the 

 colloid in the tissue to be indicative of degeneration. Guerrini 

 regards it as a normal product of secretion. Schonemann, 

 Herring, and Trautmann describe colloid masses with cell 

 remains and granules. The transitional part between the distal 

 and infundibular lobes, which goes to make up such a distinct 

 portion (Ubergangsteil) in many of the lower forms (Stendell), 

 is not present in the mammals as a strikingly different histological 

 region. In it, however, much colloid can usually be found, in 

 some forms colloid being present there when it is absent elsewhere 

 in the gland. Cushing ('12) calls attention to the more constant 

 basophilic character of the colloid in the pars juxtaneuralis, 

 while after passing into the pars neuralis it forms acidophile 

 hyaline masses. Herring states that colloid in the cleft is rare 

 and that it is never found very far distant from the nervous lobe. 

 Stendell describes secretory matter in the lumen and suggests 

 that it may represent a reserve supply. 



Peremeschko ('67) calls attention to cilia which line the resid- 

 ual lumen in man. Lothringer ('86) and Stieda ('90) describe 

 them lining the cysts. Vanderburgh ('17), in guinea-pigs, 

 found unmistakable patches of cilia lining the residual lumen 



